ArticleBMC pulmonary medicine2021
Underdiagnosis of obstructive lung disease: findings from the French CONSTANCES cohort.
Article in BMC pulmonary medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 17 citations in OpenAlex.
- Regional disparities in access to spirometry in the Brazilian public health system.Respiratory research & clinical practice · 2026Observational
- Co-occurrence of bronchiectasis, airway wall thickening, and emphysema in Chinese low-dose CT screening.European radiology · 2025Article
- Twelve barriers to COPD diagnosis in France: a comparative qualitative study.BMJ open respiratory research · 2025Article
- Global, regional, and national burden of young COPD, 1990-2021, with forecasts to 2050: a systematic analysis for the global burden of disease study 2021.BMC public health · 2025Article
- Factors associated with undiagnosed COPD in patients hospitalised for severe COPD exacerbation.BMJ open respiratory research · 2024Article
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- Swiss Cohort & Biobank - The White Paper.Public health reviews · 2022Article
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Authors and funding
8 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe burden of undiagnosed obstructive lung disease (OLD) (mainly asthma and chronic obstructive pulmonary disease) is not fully established, and targets for corrective action are yet to be identified. We assessed the underdiagnosis of OLD and its determinants in France.
methodsCONSTANCES is a French population-based cohort of adults aged 18-69 years at inception. We analysed data collected at inclusion in 2013-2014. Undiagnosed OLD was defined as spirometry-confirmed airflow limitation (FEV
resultsSpirometry results were available for 19,398 participants. The prevalence of airflow limitation was 4.6%. Overall, 64.4% of adults with airflow limitation did not report a previous diagnosis of OLD. Individuals with high cumulative tobacco consumption (≥ 10 pack-years) (aPR: 1.72 [1.28-2.32]), without respiratory symptoms (aPR: 1.51 [1.28-1.78]), and with preserved lung function (aPR: 1.21 [1.04-1.41] for a 10-point increase in FEV
conclusionUnderdiagnosis of OLD is very common among French adults, even in patients with respiratory symptoms. Efforts should be made in France to raise awareness about OLD in the general population, improve the detection of respiratory symptoms, and increase the use of spirometry among primary care professionals.
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