Evidence map›Paper›PMID 34649534›Full record

Trial reportBMC psychiatry2021

Interpersonal counselling versus perinatal-specific cognitive behavioural therapy for women with depression during pregnancy offered in routine psychological treatment services: a phase II randomised trial.

Jonathan Evans, Jenny Ingram, Roslyn Law, Hazel Taylor, Debbie Johnson, Joel Glynn, Becky Hopley, David Kessler, Jeff Round, Jenny Ford and 2 more

Open access · goldAbstract readClinical Trial, Phase IIRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Jonathan EvansPopulation Health Sciences, University of Bristol, Bristol, UK. j.evans@bristol.ac.uk.
Jenny IngramPopulation Health Sciences, University of Bristol, Bristol, UK.
Roslyn LawAnna Freud Centre, London, UK.
Hazel TaylorUniversity Hospitals Bristol and Weston NHS Trust, Bristol, UK.
Debbie JohnsonPopulation Health Sciences, University of Bristol, Bristol, UK.
Joel GlynnPopulation Health Sciences, University of Bristol, Bristol, UK.
Becky HopleyPsychology, College of Life and Environmental Sciences, University of Exeter, Exeter, UK.
David KesslerPopulation Health Sciences, University of Bristol, Bristol, UK.
Jeff RoundPopulation Health Sciences, University of Bristol, Bristol, UK.
Jenny FordAnna Freud Centre, London, UK.
Iryna CulpinPopulation Health Sciences, University of Bristol, Bristol, UK.
Heather O'MahenPsychology, College of Life and Environmental Sciences, University of Exeter, Exeter, UK.
University of Bristol · GBAnna Freud Centre · GBUniversity of Exeter · GBUniversity Hospitals Bristol and Weston NHS Foundation Trust

Funding

Wellcome Trust 212664/Z/18/Z
6 · The paper itself

Abstract

backgroundUp to one in eight women experience depression during pregnancy. In the UK, low intensity cognitive behavioural therapy (CBT) is the main psychological treatment offered for those with mild or moderate depression and is recommended during the perinatal period, however referral by midwives and take up of treatment by pregnant women is extremely low. Interpersonal Counselling (IPC) is a brief, low-intensity form of Interpersonal Psychotherapy (IPT) that focuses on areas of concern to service users during pregnancy. To improve psychological treatment for depression during pregnancy, the study aimed to assess the feasibility and acceptability of a trial of IPC for antenatal depression in routine NHS services compared to low intensity perinatal specific CBT.

methodsWe conducted a small randomised controlled trial in two centres. A total of 52 pregnant women with mild or moderate depression were randomised to receive 6 sessions of IPC or perinatal specific CBT. Treatment was provided by 12 junior mental health workers (jMHW). The primary outcome was the number of women recruited to the point of randomisation. Secondary outcomes included maternal mood, couple functioning, attachment, functioning, treatment adherence, and participant and staff acceptability.

resultsThe study was feasible and acceptable. Recruitment was successful through scanning clinics, only 6 of the 52 women were recruited through midwives. 71% of women in IPC completed treatment. Women reported IPC was acceptable, and supervisors reported high treatment competence in IPC arm by jMHWs. Outcome measures indicated there was improvement in mood in both groups (Change in EPDS score IPC 4.4 (s.d. 5.1) and CBT 4.0 (s.d. 4.8).

conclusionsThis was a feasibility study and was not large enough to detect important differences between IPC and perinatal specific CBT. A full-scale trial of IPC for antenatal depression in routine IAPT services is feasible.

trial registrationThis study has been registered with ISRCTN registry 11513120 . - date of registration 05/04/2018.

Indexed as

Cognitive Behavioral TherapyDepressive DisorderCounselingDepressionFemaleHumansPregnancyTreatment OutcomeAntenatal depressionDepressionFeasibility studyInterpersonal counsellingPregnancyPrenatal depressionRandomised controlled trial

Identifiers

PMID34649534
PMCPMC8518253
OpenAlexW3119093408

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.