Evidence map›Paper›PMID 34649508›Full record

ArticleBMC pregnancy and childbirth2021

The risk of preterm birth in combinations of socioeconomic position and mental health conditions in different age groups: a Danish nationwide register-based cohort study.

Camilla Klinge Knudsen, Amanda Marie Somer Christesen, Signe Heuckendorff, Kirsten Fonager, Martin Nygård Johansen, Charlotte Overgaard

Open access · goldAbstract read
In one paragraph

Article in BMC pregnancy and childbirth, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Camilla Klinge KnudsenDepartment of Social Medicine, Aalborg University Hospital, Havrevangen 1, 9000, Aalborg, Denmark. ca-klinge@live.dk.ORCID https://orcid.org/0000-0002-8588-7637
Amanda Marie Somer ChristesenDepartment of Social Medicine, Aalborg University Hospital, Havrevangen 1, 9000, Aalborg, Denmark.ORCID https://orcid.org/0000-0003-2691-3943
Signe HeuckendorffDepartment of Social Medicine, Aalborg University Hospital, Havrevangen 1, 9000, Aalborg, Denmark.ORCID https://orcid.org/0000-0002-4074-064X
Kirsten FonagerDepartment of Social Medicine, Aalborg University Hospital, Havrevangen 1, 9000, Aalborg, Denmark.ORCID https://orcid.org/0000-0001-9641-992X
Martin Nygård JohansenUnit of Clinical Biostatistics, Aalborg University Hospital, Aalborg, Denmark.ORCID https://orcid.org/0000-0001-9790-0985
Charlotte OvergaardPublic Health and Epidemiology Group, Department of Health Science and Technology, Aalborg University, Aalborg, Denmark.ORCID https://orcid.org/0000-0002-3370-2338
Aalborg University Hospital · DKAalborg University · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInequality in preterm birth is a world-wide challenge that has proved difficult for maternity care services to meet. Reducing the inequality requires identification of pregnant women at particularly high risk of preterm birth in order to target interventions. Therefore, the aim was to estimate the risk of preterm birth in women with different combinations of socioeconomic position, mental health conditions, and age.

methodsIn this nationwide register-based cohort study, we included all first-time mothers that gave birth to a singleton liveborn infant in Denmark between 2000 and 2016. The absolute and relative risk of preterm birth (< 37 weeks of gestation) was examined in different combinations of educational level (high, intermediate, and low) and mental health conditions (no, minor, and moderate/severe) in three age strata (≤23, 24-30, and ≥ 31 years). We estimated the relative risk using Poisson regression with a robust error variance. As additive interaction can help identify subgroups where limited resources can be of best use, we measured the attributable proportion to assess the risk that is due to interaction of the different exposures.

resultsOf the 415,523 included first-time mothers, 6.3% gave birth prematurely. The risk of preterm birth increased with decreasing educational level and increasing severity of mental health conditions in all age strata, but most in women aged ≥31 years. The highest absolute risk was 12.9% [95% CI: 11.2;14.8%] in women aged ≥31 years with low education and moderate/severe mental health conditions resulting in a relative risk of 2.23 [95% CI: 1.93-2.58] compared to the unexposed reference group in that age strata. We found positive additive interaction between low education and mental health conditions in women aged 24-30 and ≥ 31 years and between age ≥ 31 years and combinations of mental health conditions and educational levels.

conclusionThe inequality in preterm birth increased with increasing age. To reduce inequality in preterm birth focused attention on women with higher age further combined with lower educational levels and mental health conditions is essential.

Indexed as

Social ClassAdultCohort StudiesDenmarkEducational StatusFemaleGestational AgeHumansMental DisordersPregnancyPregnancy ComplicationsPremature BirthRegistriesRisk FactorsYoung AdultAdditive interactionBirth outcomeEducational levelInequalityMaternal ageMaternal mental healthMental health conditionsPregnancyPreterm birthSocioeconomic position

Identifiers

PMID34649508
PMCPMC8515728
OpenAlexW3201160356

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.