ArticleCancer control : journal of the Moffitt Cancer Center
Clinicopathological Features and Survival of Adolescent and Young Adults with Cervical Cancer.
Article in Cancer control : journal of the Moffitt Cancer Center. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed, 12 citations in OpenAlex.
- Social inequities and clinical outcomes in young women with cervical cancer: Real-world evidence.PloS one · 2026Article
- Menstrual, reproductive, and contraceptive factors associated with cervical cancer in women aged ≤35 years: an individually matched case-control study.Frontiers in oncology · 2026Article
- Article
- A nomogram for predicting prognosis for young cervical neuroendocrine carcinoma: A SEER-based study and external validation.Frontiers in oncology · 2025Article
- Global, regional, and national burden of ovarian cancer among young women during 1990-2019.European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) · 2025Article
- Construction and validation of prognostic models for young cervical cancer patients: age stratification based on restricted cubic splines.Scientific reports · 2024Article
- Patient delay and related influencing factors in Chinese women under 35 years diagnosed with cervical cancer: A cross-sectional study.Asia-Pacific journal of oncology nursing · 2023Article
- Identification of Specific Cervical Cancer Subtypes and Prognostic Gene Sets in Tumor and Nontumor Tissues Based on GSVA Analysis.Journal of oncology · 2022Article
- Epidemiological trends of female breast and gynecologic cancers in adolescents and young adults in China from 1990 to 2019: Results from the Global Burden of Disease Study 2019.Frontiers in oncology · 2022Article
- Human Papilloma Virus Infection and Gene Subtypes Analysis in Women Undergoing Physical Examinations: A 2015-2020 Study in Wenzhou, China.Cancer control : journal of the Moffitt Cancer CenterArticle
- Competitive Risk Model Nomogram to Predict Prognosis in Patients Aged Over 65 Years with nonmetastatic Cervical Cancer: A SEER Population-Based Study.Technology in cancer research & treatmentArticle
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5 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
purposeTo explore clinicopathological characteristics and their prognostic value among young patients with cervical cancer (who are aged ≤25 years old).
methodsThe Surveillance, Epidemiology, and End Results Program (SEER) database was used to extract data on cervical cancer patients. They were then stratified by age as young women (≤25 years old) and old women (26-35 years old) and analyzed for clinicopathology characteristics and treatment modalities. Prognosis was analyzed using Kaplan-Meier survival curve, as well as hazard ratios using Cox regression modeling. The nomogram was developed based on Cox hazards regression model.
resultsCompared to 26-35 years old women, patients aged ≤25 years tended to be white ethnicity, unmarried, had earlier stage of disease. There was also a better prognosis among younger cohort. Grade, FIGO stage, histologic subtypes, and surgical modalities influenced the survival outcomes of young patients. Among young cohorts, surgery prolonged the survival time of IA-IIA stage patients while surgical and non-surgical management presented no statistically prognostic difference among patients at IIB-IVB stage. Besides, the nomogram which constructed according to Cox hazards regression model which contained independent prognosis factors including FIGO stage, surgery type, and histologic type of tumor can robustly predict survival of young patients.
conclusionCervical cancer patients ≤25 years old were uncommon and lived longer than the older patients. Among these young patients at IA-IIA stage, surgical treatment could be more effective at preventing death than non-surgery. The nomogram could perfectly predict the prognosis of young adults and adolescents with cervical cancer.
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