Evidence map›Paper›PMID 34648414›Full record

SynthesisThe Journal of international medical research2021

XRCC2 Arg188His polymorphism and colorectal cancer risk: a meta-analysis.

Zhiyu Wang, Yaning Wei, Lin An, Chenglin Xi, Kunjie Wang, Dan Hong, Yan Shi, Aiming Zang, Shenyong Su, Wenwen Li

Open access · goldAbstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in The Journal of international medical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Zhiyu WangDepartment of Medical Oncology, Affiliated Hospital of Hebei University, Baoding, Hebei Province, China.
Yaning WeiDepartment of Medical Oncology, Affiliated Hospital of Hebei University, Baoding, Hebei Province, China.
Lin AnDepartment of Medical Oncology, Affiliated Hospital of Hebei University, Baoding, Hebei Province, China.
Chenglin XiDepartment of Medical Oncology, Affiliated Hospital of Hebei University, Baoding, Hebei Province, China.
Kunjie WangDepartment of Medical Oncology, Affiliated Hospital of Hebei University, Baoding, Hebei Province, China.
Dan HongDepartment of Medical Oncology, Affiliated Hospital of Hebei University, Baoding, Hebei Province, China.
Yan ShiDepartment of Medical Oncology, Affiliated Hospital of Hebei University, Baoding, Hebei Province, China.
Aiming ZangDepartment of Medical Oncology, Affiliated Hospital of Hebei University, Baoding, Hebei Province, China.
Shenyong SuDepartment of Medical Oncology, Affiliated Hospital of Hebei University, Baoding, Hebei Province, China.ORCID https://orcid.org/0000-0001-7985-8998
Wenwen LiDepartment of Medical Oncology, Affiliated Hospital of Hebei University, Baoding, Hebei Province, China.
Affiliated Hospital of Hebei University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the potential correlation between the Arg188His (rs3218536) polymorphism of X-ray repair cross-complementing 2 (

methodsThe CNKI, PubMed, EMBASE and Cochrane library databases were systematically searched for relevant studies published up to July 2021. Data were extracted from included studies, and analysed for pooled or subgroup odds ratios (ORs) with 95% confidence intervals (CIs) using STATA 12.0 software.

resultsSeven published studies were included. Pooled analysis revealed that the

conclusionThe current meta-analysis suggests that the

Indexed as

Colorectal NeoplasmsComplement C2DNA-Binding ProteinsGenetic Predisposition to DiseaseHumansPolymorphism, Single NucleotideRisk FactorsX-RaysComplement C2DNA-Binding ProteinsXRCC2 protein, humancancercancer riskmeta-analysispolymorphismrs3218536XRCC2

Identifiers

PMID34648414
PMCPMC8521768
OpenAlexW3207524958

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.