Evidence map›Paper›PMID 34648330›Full record

ArticleScience (New York, N.Y.)2021

Astrocyte Ca

Jonathan Lezmy, I Lorena Arancibia-Cárcamo, Tania Quintela-López, Diane L Sherman, Peter J Brophy, David Attwell

Abstract read
In one paragraph

Article in Science (New York, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed.

  1. Review
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  14. Article
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  16. Article
  17. Review
  18. Review
  19. Article
  20. Adenosine ABiological psychiatry · 2025
    Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jonathan LezmyDepartment of Neuroscience, Physiology and Pharmacology, University College London, London WC1E 6BT, UK.ORCID 0000-0002-6401-0131
I Lorena Arancibia-CárcamoDepartment of Neuroscience, Physiology and Pharmacology, University College London, London WC1E 6BT, UK.ORCID 0000-0002-0624-3850
Tania Quintela-LópezDepartment of Neuroscience, Physiology and Pharmacology, University College London, London WC1E 6BT, UK.ORCID 0000-0002-0624-8408
Diane L ShermanCentre for Discovery Brain Sciences, University of Edinburgh, Edinburgh EH16 4SB, UK.
Peter J BrophyCentre for Discovery Brain Sciences, University of Edinburgh, Edinburgh EH16 4SB, UK.
David AttwellDepartment of Neuroscience, Physiology and Pharmacology, University College London, London WC1E 6BT, UK.ORCID 0000-0003-3618-0843

Funding

Wellcome Trust 099222Wellcome Trust 107008Wellcome Trust 219366
6 · The paper itself

Abstract

In the brain’s gray matter, astrocytes regulate synapse properties, but their role is unclear for the white matter, where myelinated axons rapidly transmit information between gray matter areas. We found that in rodents, neuronal activity raised the intracellular calcium concentration ([Ca

Indexed as

Cortical ExcitabilityNeural ConductionAction PotentialsAdenosine TriphosphateAnimalsAstrocytesAxonsCalciumMiceMice, TransgenicPatch-Clamp TechniquesRatsRats, Sprague-DawleyAdenosine TriphosphateCalcium

Identifiers

PMID34648330
PMCPMC7611967

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.