Evidence map›Paper›PMID 34648142›Full record

ReviewActa neurologica Belgica2021

Clinical management of pediatric chordomas: a comprehensive review.

Taylor Reardon, Caleb Marsh, Preston Rippe, Donatas Ruzys, Benjamin Ayres, David Cline, Brian Fiani

Abstract readReview
PubMed Publisher
In one paragraph

Review in Acta neurologica Belgica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Taylor ReardonKentucky College of Osteopathic Medicine, University of Pikeville, Pikeville, KY, USA. taylorreardon@upike.edu.ORCID http://orcid.org/0000-0002-1179-0111
Caleb MarshKentucky College of Osteopathic Medicine, University of Pikeville, Pikeville, KY, USA.
Preston RippeKentucky College of Osteopathic Medicine, University of Pikeville, Pikeville, KY, USA.
Donatas RuzysKentucky College of Osteopathic Medicine, University of Pikeville, Pikeville, KY, USA.
Benjamin AyresKentucky College of Osteopathic Medicine, University of Pikeville, Pikeville, KY, USA.
David ClineKentucky College of Osteopathic Medicine, University of Pikeville, Pikeville, KY, USA.
Brian FianiDepartment of Neurosurgery, Desert Regional Medical Center, Palm Springs, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chordomas are malignant tumors derived from remnants of the notochord. These are extremely rare in pediatric patients, accounting for approximately 5% of all chordomas, with most lesions occupying the cranium. Chordomas also can occupy all levels of the spine, demonstrating a broad spectrum of neurologic presentation. Optimal treatment aims for gross total resection with accompanying radiation therapy to prevent recurrence. Their aggressive and infiltrative nature makes clinical management challenging, involving multiple disciplines and close monitoring to ensure optimal outcomes. This comprehensive review aims to cover the genetics, demographics, pathogenesis, neurologic sequelae, radiological considerations, chemotherapeutic management, surgical management, and post-operative considerations of pediatric chordoma patients.

Indexed as

Disease ManagementAntineoplastic AgentsBrain NeoplasmsChildChordomaHumansSpinal Cord NeoplasmsAntineoplastic AgentsChordomaNeurosurgeryPediatric chordomaPediatric neurosurgery

Identifiers

PMID34648142

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.