Evidence map›Paper›PMID 34648136›Full record

ReviewJournal of gastrointestinal cancer2022

Pancreaticobiliary Malignancies in the Emergency Room: Management of Acute Complications and Oncological Emergencies.

Konstantinos Kamposioras, Joe Geraghty, Jordan Appleyard, Mohammed Dawod, Konstantinos Papadimitriou, Angela Lamarca, Alan Anthoney

Abstract readReview
In one paragraph

Review in Journal of gastrointestinal cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Konstantinos KamposiorasThe Christie NHS Foundation Trust, Manchester, Greater Manchester, UK.
Joe GeraghtyDepartment of Gastroenterology, Manchester Royal Infirmary, Manchester, UK.
Jordan AppleyardSt James' University Hospital, LS9 7TF, Leeds, UK.
Mohammed DawodThe Christie NHS Foundation Trust, Manchester, Greater Manchester, UK.
Konstantinos PapadimitriouEarly Clinical Trials Unit, Antwerp University Hospital, Antwerp, Belgium.
Angela LamarcaThe Christie NHS Foundation Trust, Manchester, Greater Manchester, UK.
Alan AnthoneyLeeds Institute of Medical Research, St James' Institute of Oncology, St James' University Hospital, University of Leeds, Leeds, LS9 7TF, UK. alan.anthoney@nhs.net.ORCID http://orcid.org/0000-0001-5695-8312

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundManagement of pancreaticobiliary (PB) malignancies remains a clinical challenge. In this review, we focus on the management of oncological emergencies in PB malignancies and the potential complication of associated therapeutic interventions.

methodsBiobliographic review of current evidence on the management of oncological emergencies, their potential complications, as well as synthesis of recommendations was performed. The pathogenesis, frequency, related symptoms as well as appropriate investigations are presented.

resultsThe oncologic emergencies in PB patients were summarised in six categories: (1) hematological (including febrile neutropaenia, thrombocytopenia, coagulopathies), (2) gastrointestinal (gastric outlet and biliary obstruction, gastrointestinal bleeding), (3) thromboembolic events, (4) ascites, (5) metabolic disorders and (6) neurologic complications. The pathogenesis, frequency, related symptoms as well as appropriate investigations are also presented.

conclusionPatients with PB malignancies are at increased risk of a wide variation of medical emergencies. Clinical knowledge, early recognition and collaboration with the relevant specialties are critical to manage these complications effectively, tailoring overall management around the actual prognosis and individuals' expectations.

Indexed as

EmergenciesNeoplasmsEmergency Service, HospitalHumansMedical OncologyPrognosisCholangiocarcinomaComplicationsEmergenciesGall bladder cancerManagementPancreatic cancer

Identifiers

PMID34648136
PMCPMC9630225

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.