Evidence map›Paper›PMID 34648129›Full record

ArticleCerebellum (London, England)2022

"A Great Reinforcing Organ": the Cerebellum According to Silas Weir Mitchell.

Lazaros C Triarhou, Mario Manto

Abstract readHistorical Article
PubMed Publisher
In one paragraph

Article in Cerebellum (London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 84% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Lazaros C TriarhouLaboratory of Theoretical and Applied Neuroscience, University of Macedonia, Egnatia 156, Bldg. Z-312, 54636, Thessaloniki, Greece. triarhou@uom.edu.gr.ORCID http://orcid.org/0000-0001-6544-5738
Mario MantoUnité Des Ataxies Cérébelleuses, CHU-Charleroi, Charleroi, Belgium.ORCID http://orcid.org/0000-0001-6034-4380
University of Macedonia · GRUniversity of Mons · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This Cerebellar Classic highlights a work by the physician and novelist, Silas Weir Mitchell (1829-1914), a pupil of Claude Bernard and a founding father of American neurology. Published in the aftermath of the American Civil War, the article reported observations on cerebellar physiology based on ablation and tissue freezing experiments in pigeons, rabbits, and guinea pigs. Mitchell communicated his results before the Academy of Natural Sciences of Philadelphia, and proposed a general theory of the cerebellum as an augmenting and reinforcing organ to the cerebrospinal motor system. After reviewing and contrasting previous theories of Flourens and Bouillaud, Mitchell formulated his own theory, which was in line with the views of Rolando and Luys. The theory emphasized the necessity, initially suggested by Brown-Séquard, of distinguishing between phenomena due to loss of function and those due to irritation as a central principle that should guide any physiological research.

Indexed as

NeurologyAnimalsCerebellumGuinea PigsHistory, 19th CenturyHistory, 20th CenturyRabbitsAmerican Physiological SocietyCerebellar physiologyHistory of neurologySilas Weir Mitchell (1829–1914)

Identifiers

PMID34648129
OpenAlexW3207871114

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.