Evidence map›Paper›PMID 34647827›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2021

Positive expiratory pressure: a potential therapy to mitigate acute bronchoconstriction in the asthma of obesity.

Swati A Bhatawadekar, Anne E Dixon, Ubong Peters, Nirav Daphtary, Kevin Hodgdon, David A Kaminsky, Jason H T Bates

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Swati A BhatawadekarPulmonary Disease and Critical Care Medicine, University of Vermont College of Medicine, Burlington, Vermont.
Anne E DixonPulmonary Disease and Critical Care Medicine, University of Vermont College of Medicine, Burlington, Vermont.
Ubong PetersPulmonary Disease and Critical Care Medicine, University of Vermont College of Medicine, Burlington, Vermont.ORCID 0000-0002-2491-9519
Nirav DaphtaryPulmonary Disease and Critical Care Medicine, University of Vermont College of Medicine, Burlington, Vermont.
Kevin HodgdonPulmonary Disease and Critical Care Medicine, University of Vermont College of Medicine, Burlington, Vermont.
David A KaminskyPulmonary Disease and Critical Care Medicine, University of Vermont College of Medicine, Burlington, Vermont.
Jason H T BatesPulmonary Disease and Critical Care Medicine, University of Vermont College of Medicine, Burlington, Vermont.ORCID 0000-0002-6062-6377
University of Vermont · US

Funding

Non-Allergic Late-Onset Asthma of Obesity: Pathophysiology and TherapyR01HL130847 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI BATES, JASON HT, DIXON, ANNE E · 2016 to 2019
$2.3M
NHLBI NIH HHS HL-130847NHLBI NIH HHS R01 HL130847
6 · The paper itself

Abstract

Late-onset nonallergic (LONA) asthma in obesity is characterized by increased peripheral airway closure secondary to abnormally collapsible airways. We hypothesized that positive expiratory pressure (PEP) would mitigate the tendency to airway closure during bronchoconstriction, potentially serving as rescue therapy for LONA asthma of obesity. The PC

Indexed as

AsthmaBronchoconstrictionBronchial Provocation TestsFemaleForced Expiratory VolumeHumansMethacholine ChlorideObesityMethacholine Chloridelate-onset nonallergic asthmalung volumeobese asthmaobesitypositive expiratory pressure

Identifiers

PMID34647827
PMCPMC8714981
OpenAlexW3206919757

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.