Evidence map›Paper›PMID 34647770›Full record

ArticleBehavioral neuroscience2022

Noradrenergic regulation of two-armed bandit performance.

Kyra Swanson, Bruno B Averbeck, Mark Laubach

Abstract read
In one paragraph

Article in Behavioral neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kyra SwansonDepartment of Neuroscience.
Bruno B AverbeckLaboratory of Neuropsychology.
Mark LaubachDepartment of Neuroscience.ORCID 0000-0002-2403-4497

Funding

Frontal Striatal Systems and Dopamine in Normal and Pathological BehaviorZIAMH002928 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI AVERBECK, BRUNO · 2010 to 2025
$29.0M
American UniversityIntramural NIH HHS ZIA MH002928
6 · The paper itself

Abstract

Reversal learning depends on cognitive flexibility. Many reversal learning studies assess cognitive flexibility based on the number of reversals that occur over a test session. Reversals occur when an option is repeatedly chosen, e.g., eight times in a row. This design feature encourages win-stay behavior and thus makes it difficult to understand how win-stay decisions influence reversal performance. We used an alternative design, reversals over blocks of trials independent of performance, to study how perturbations of the medial orbital cortex and the noradrenergic system influence reversal learning. We found that choice accuracy varies independently of win-stay behavior and the noradrenergic system controls sensitivity to positive feedback during reversal learning. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

Indexed as

Reversal LearningRewardPrefrontal Cortex

Identifiers

PMID34647770
PMCPMC9623600

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.