Evidence map›Paper›PMID 34647751›Full record

ArticleNano letters2021

Divalent Multilinking Bonds Control Growth and Morphology of Nanopolymers.

Yan Xiong, Zhiwei Lin, Deniz Mostarac, Brian Minevich, Qiuyuan Peng, Guolong Zhu, Pedro A Sánchez, Sofia Kantorovich, Yonggang Ke, Oleg Gang

Abstract read
In one paragraph

Article in Nano letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yan XiongDepartment of Chemical Engineering, Columbia University, New York, New York 10027, United States.ORCID 0000-0001-9636-6127
Zhiwei LinDepartment of Chemical Engineering, Columbia University, New York, New York 10027, United States.ORCID 0000-0001-9194-1145
Deniz MostaracComputational and Soft Matter Physics, Faculty of Physics, University of Vienna, Boltzmanngasse 5, 1090 Vienna, Austria.
Brian MinevichDepartment of Chemical Engineering, Columbia University, New York, New York 10027, United States.
Qiuyuan PengDepartment of Applied Physics and Applied Mathematics, Columbia University, New York, New York 10027, United States.
Guolong ZhuDepartment of Chemical Engineering, Columbia University, New York, New York 10027, United States.
Pedro A SánchezComputational and Soft Matter Physics, Faculty of Physics, University of Vienna, Boltzmanngasse 5, 1090 Vienna, Austria.
Sofia KantorovichComputational and Soft Matter Physics, Faculty of Physics, University of Vienna, Boltzmanngasse 5, 1090 Vienna, Austria.
Yonggang KeWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia 30322, United States.ORCID 0000-0003-1673-2153
Oleg GangDepartment of Chemical Engineering, Columbia University, New York, New York 10027, United States.ORCID 0000-0001-5534-3121

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Assembly of nanoscale objects into linear architectures resembling molecular polymers is a basic organization resulting from divalent interactions. Such linear architectures occur for particles with two binding patches on opposite sides, known as Janus particles. However, unlike molecular systems where valence bonds can be envisioned as pointlike interactions nanoscale patches are often realized through multiple molecular linkages. The relationship between the characteristics of these linkages, the resulting interpatch connectivity, and assembly morphology is not well-explored. Here, we investigate assembly behavior of model divalent nanomonomers, DNA nanocuboid with tailorable multilinking bonds. Our study reveals that the characteristics of individual molecular linkages and their collective properties have a profound effect on nanomonomer reactivity and resulting morphologies. Beyond linear nanopolymers, a common signature of divalent nanomonomers, we observe an effective valence increase as linkages lengthened, leading to the nanopolymer bundling. The experimental findings are rationalized by molecular dynamics simulations.

Indexed as

DNAPolymersMolecular Dynamics SimulationDNAPolymersDNA nanotechnologyPatchy particlesphase behaviorpolymerizationself-assembly

Identifiers

PMID34647751
PMCPMC8704199

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.