Evidence map›Paper›PMID 34647649›Full record

SynthesisAddiction (Abingdon, England)2022

Effects of brief substance use interventions delivered in general medical settings: a systematic review and meta-analysis.

Emily E Tanner-Smith, Nicholas J Parr, Maria Schweer-Collins, Richard Saitz

Registry-linked trialOpen access · greenAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Addiction (Abingdon, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07118826 (Evaluation and Refinement of a Trauma-Informed and Peer Supported Mobile Brief Intervention for Young Adult Substance Users With Interpersonal Trauma), which is not on this map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07118826 nawithdrawnnot on this mapstarted 2025, after this paper: background citation

Evaluation and Refinement of a Trauma-Informed and Peer Supported Mobile Brief Intervention for Young Adult Substance Users With Interpersonal Trauma

TypeinterventionalSponsorWestern Kentucky UniversityRan2025 to 2027Enrolled0ConditionsHeavy Drinking, Alcohol Drinking, Substance Use, Drinking BehaviorArmsStandard Brief Intervention, Trauma-Informed and Peer-Supported Brief Intervention
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.

  1. Brief Drug Interventions Delivered in General Medical Settings: a Systematic Review and Meta-analysis of Cannabis Use Outcomes.Prevention science : the official journal of the Society for Prevention Research · 2025
    Pooled it
  2. Investigating for Whom Brief Substance Use Interventions Are Most Effective: An Individual Participant Data Meta-analysis.Prevention science : the official journal of the Society for Prevention Research · 2023
    Pooled it
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Emily E Tanner-SmithCounseling Psychology and Human Services Department, University of Oregon, College of Education, Eugene, OR, USA.ORCID 0000-0002-5313-0664
Nicholas J ParrCounseling Psychology and Human Services Department, University of Oregon, College of Education, Eugene, OR, USA.ORCID 0000-0003-2067-9500
Maria Schweer-CollinsCounseling Psychology and Human Services Department, University of Oregon, College of Education, Eugene, OR, USA.ORCID 0000-0001-8285-9107
Richard SaitzDepartment of Community Health Sciences, Boston University School of Public Health, Boston, MA, USA.ORCID 0000-0002-2535-1427
University of Oregon · USBoston University · USUnited States Department of Veterans Affairs · US

Funding

Brief Substance Use Interventions in General Healthcare Settings: Understanding Variability in EffectsR01DA043589 · NIDA · UNIVERSITY OF OREGON · PI TANNER-SMITH, EMILY E. · 2017 to 2018
$444k
NIDA NIH HHS R01 DA043589
6 · The paper itself

Abstract

aimsTo estimate effects of brief substance use interventions delivered in general medical settings.

methodsA systematic review and meta-analysis of randomized trials conducted since 1990 of brief substance use interventions in patients of any age or severity level recruited in general medical settings. Primary outcomes were any measure of substance use or substance-related consequences (indexed with Hedges' g and risk ratios). Mixed-effects meta-regressions were used to estimate overall effects and predictors of effect variability. Analyses were conducted separately by brief intervention (BI) target substance: alcohol only or drugs.

findingsA total of 116 trials (64 439 participants) were identified; 111 (62 263 participants) provided effect size data and were included in the meta-analysis. Drug-targeted BIs yielded significant small improvements in multiple drug/mixed substance use (Hedges' g

conclusionsWhen delivered in general medical settings, alcohol-targeted brief interventions may produce small beneficial reductions in drinking (equivalent to a reduction in 1 drinking day per month). There is limited evidence regarding the effects of drug-targeted brief interventions on drug use.

Indexed as

Crisis InterventionSubstance-Related DisordersAlcohol DrinkingCounselingEthanolHumansEthanolBrief interventionemergency departmentmeta-analysisprimary caresystematic review

Identifiers

PMID34647649
PMCPMC8904275
OpenAlexW3206867129

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.