Evidence map›Paper›PMID 34647634›Full record

ArticleJournal of medical virology2022

Introduction of SARS-CoV-2 C.37 (WHO VOI lambda) in the Sao Paulo State, Southeast Brazil.

Simone Kashima, Svetoslav N Slavov, Marta Giovanetti, Evandra S Rodrigues, José S L Patané, Vincent L Viala, Elaine V Santos, Mariane Evaristo, Loyze P O de Lima, Antonio J Martins and 30 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medical virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
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  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

40 authors.

Simone KashimaBlood Center of Ribeirão Preto, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.ORCID 0000-0002-1487-0141
Svetoslav N SlavovBlood Center of Ribeirão Preto, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
Marta GiovanettiInstituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Evandra S RodriguesBlood Center of Ribeirão Preto, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
José S L PatanéButantan Institute, São Paulo, Brazil.
Vincent L VialaButantan Institute, São Paulo, Brazil.
Elaine V SantosBlood Center of Ribeirão Preto, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
Mariane EvaristoBlood Center of Ribeirão Preto, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
Loyze P O de LimaButantan Institute, São Paulo, Brazil.
Antonio J MartinsButantan Institute, São Paulo, Brazil.
Claudia R Dos Santos BarrosButantan Institute, São Paulo, Brazil.
Elaine C MarquezeButantan Institute, São Paulo, Brazil.
Pedro M M GaribaldiRibeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
Natasha N FerreiraSerrana State Hospital, Serrana, Brazil.
Glenda R MoraesEpidemic Service, Serrana, Brazil.
Ricardo A BrassalotiCentro de Genômica Funcional da ESALQ, University of São Paulo, Piracicaba, SP, Brazil.
Raquel L R C CassanoCentro de Genômica Funcional da ESALQ, University of São Paulo, Piracicaba, SP, Brazil.
Pilar D S C MarianiNGS Soluções Genômicas, Piracicaba, SP, Brazil.
João P KitajimaMendelics Análise Genômica SA, Sao Paulo, Brazil.
David SchlesingerMendelics Análise Genômica SA, Sao Paulo, Brazil.
Rafael S BezerraBlood Center of Ribeirão Preto, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
Patricia A AssatoDepartment of Bioprocesses and Biotechnology, School of Agricultural Sciences, São Paulo State University (UNESP), Botucatu, Brazil.
Felipe A S da CostaDepartment of Bioprocesses and Biotechnology, School of Agricultural Sciences, São Paulo State University (UNESP), Botucatu, Brazil.
Mirele Daiana PoletiDepartment of Veterinary Medicine, School of Animal Science and Food Engineering, University of Sao Paulo, Pirassununga, Brazil.
Jessika C C LesbonDepartment of Veterinary Medicine, School of Animal Science and Food Engineering, University of Sao Paulo, Pirassununga, Brazil.
Elisangela C MattosDepartment of Veterinary Medicine, School of Animal Science and Food Engineering, University of Sao Paulo, Pirassununga, Brazil.
Cecilia A BanhoMedicine School of São José do Rio Preto (FAMERP), São José do Rio Preto, São Paulo, Brazil.
Lívia SacchettoMedicine School of São José do Rio Preto (FAMERP), São José do Rio Preto, São Paulo, Brazil.
Rejane M T GrottoSchool of Agricultural Sciences, São Paulo State University (UNESP), Botucatu, Brazil.
Jayme A Souza-NetoSchool of Agricultural Sciences, São Paulo State University (UNESP), Botucatu, Brazil.
Vagner FonsecaInstituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.ORCID 0000-0001-5521-6448
Luiz C J de AlcantaraInstituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Maurício L NogueiraMedicine School of São José do Rio Preto (FAMERP), São José do Rio Preto, São Paulo, Brazil.ORCID 0000-0003-1102-2419
Heidge FukumasuDepartment of Veterinary Medicine, School of Animal Science and Food Engineering, University of Sao Paulo, Pirassununga, Brazil.
Luiz L CoutinhoCentro de Genômica Funcional da ESALQ, University of São Paulo, Piracicaba, SP, Brazil.
Marcos BorgesRibeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
Rodrigo T CaladoBlood Center of Ribeirão Preto, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
Maria C EliasButantan Institute, São Paulo, Brazil.
Sandra C SampaioButantan Institute, São Paulo, Brazil.
Dimas T CovasBlood Center of Ribeirão Preto, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Lambda variants of interest (VOI) (C37/GR/452Q.V1/21G) was initially reported in Lima, Peru but has gained rapid dissemination through other Latin American countries. Nevertheless, the dissemination and molecular epidemiology of the Lambda VOI in Brazil is unknown apart from a single case report. In this respect, we characterized the circulation of the SARS-CoV-2 Lambda VOI (C37/GR/452Q.V1/21G) in Sao Paulo State, Brazil. From March to June 2021, we identified seven Lambda isolates in a set of approximately 8000 newly sequenced genomes of the Network for Pandemic Alert of Emerging SARS-CoV-2 variants from Sao Paulo State. Interestingly, in three of the positive patients, the Lambda VOI infection was probably related to a contact transmission. These individuals were fully vaccinated to COVID-19 and presented mild symptoms. The remaining positive for Lambda VOI individuals showed different levels of COVID-19 symptoms and one of them needed hospitalization (score 5, WHO). In our study, we present a low level of Lambda VOI circulation in the Sao Paulo State. This reinforces the essential role of molecular surveillance for the effective SARS-CoV-2 pandemic response, especially in regard to circulating variants.

Indexed as

COVID-19SARS-CoV-2BrazilHumansWorld Health OrganizationLambda variantmolecular epidemiologySARS-CoV-2 variantsvariants of interest

Identifiers

PMID34647634
PMCPMC8662236

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.