Evidence map›Paper›PMID 34647229›Full record

Observational studyJournal of general internal medicine2022

Observational study of patient characteristics associated with a timely diagnosis of dementia and mild cognitive impairment without dementia.

Lindsay White, Bailey Ingraham, Eric Larson, Paul Fishman, Sungchul Park, Norma B Coe

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in Journal of general internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 41 citations in OpenAlex.

  1. Trial
  2. Observational
  3. Identification of prevalent dementia in Medicare Advantage encounters, compared with rigorous cohort assessments.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Article
  4. Article
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  6. Performance of ICD-10 code-based dementia case definition in the Health and Retirement Study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
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  12. Review
  13. Does Frailty Predict Cognitive and Functional Deficits After Nine Years?International journal of geriatric psychiatry · 2025
    Article
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  15. Article
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  17. Article
  18. Considerations for widespread implementation of blood-based biomarkers of Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  19. Article
  20. Mapping racial and ethnic healthcare disparities for persons living with dementia: A scoping review.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Lindsay WhiteCenter for Health Care Quality and Outcomes, RTI International, Seattle, WA, USA.ORCID 0000-0002-5298-3059
Bailey IngrahamSchool of Public Health, University of Washington, Seattle, WA, USA.
Eric LarsonKaiser Permanente Washington Health Research Institute, Seattle, WA, USA.
Paul FishmanSchool of Public Health, University of Washington, Seattle, WA, USA.
Sungchul ParkDornsife School of Public Health, Drexel University, Philadelphia, PA, USA.
Norma B CoePerelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
University of Washington · USDrexel University · USKaiser Permanente Washington Health Research Institute · USNational Bureau of Economic Research · USRTI International · US

Funding

STATISTICAL DATA ENCLAVE COREP30AG012836 · NIA · UNIVERSITY OF PENNSYLVANIA · PI COE, NORMA B, KOHLER, HANS-PETER · 1999 to 2024
$14.0M
Current and Future Costs of Alzheimer's and Dementia CareR01AG049815 · NIA · UNIVERSITY OF WASHINGTON · PI COE, NORMA B · 2015 to 2018
$2.1M
NIA NIH HHS P30 AG012836NIA NIH HHS R01 AG049815
6 · The paper itself

Abstract

backgroundTimely diagnosis of cognitive impairment is a key goal of the National Plan to Address Alzheimer's Disease, but studies of factors associated with a timely diagnosis are limited.

objectiveTo identify patient characteristics associated with a timely diagnosis of dementia and mild cognitive impairment (MCI).

designRetrospective observational study using survey data from the Health and Retirement Study (HRS) from 1995-2016 (interview waves 3-13).

participants4,760 respondents with incident dementia and 1,864 with incident MCI identified using longitudinal measures of cognitive functioning. MAIN MEASURES: Timely or delayed diagnosis based on the timing of a self or proxy report of a healthcare provider diagnosis in relation to respondents first dementia or MCI-qualifying cognitive score, sociodemographic characteristics, health status, health care utilization, insurance provider, and year of first qualifying score. KEY

resultsOnly 26.0% of the 4,760 respondents with incident dementia and 11.4% of the 1,864 respondents with incident MCI received a timely diagnosis. Non-Hispanic Black respondents and respondents with less than a college degree were significantly less likely to receive a timely diagnosis of either dementia or MCI than Non-Hispanic White respondents (dementia odds ratio (OR): 0.61, 95% CI: 0.50, 0.75; MCI OR: 0.40, 95% CI: 0.23, 0.70) and those with a college degree (dementia OR for less than high school degree: 0.30, 95% CI: 0.23, 0.38; MCI OR: 0.36, 95% CI: 0.22, 0.60). Respondents that lived alone were also less likely to receive a timely diagnosis of dementia (OR: 0.69, 95% CI: 0.59, 0.81), though not MCI. Timely diagnosis of both conditions increased over time.

conclusionsTargeting resources for timely diagnosis of cognitive impairment to individuals from racial and ethnic minorities, lower educational attainment, and living alone may improve detection and reduce disparities around timely diagnosis of dementia and MCI.

Indexed as

Alzheimer DiseaseCognitive DysfunctionCognitionDisease ProgressionHumansSurveys and Questionnairescognitive impairmentdementiadiagnosisdisparities

Identifiers

PMID34647229
PMCPMC9485306
OpenAlexW3206483938

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.