Evidence map›Paper›PMID 34647006›Full record

ArticleInfection prevention in practice2021

Carbapenem-resistant Enterobacterales colonization and subsequent infection in a neonatal intensive care unit in Shanghai, China.

L Yin, L He, J Miao, W Yang, X Wang, J Ma, N Wu, Y Cao, C Wang

Open access · goldAbstract read
In one paragraph

Article in Infection prevention in practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Carbapenem-resistantFrontiers in cellular and infection microbiology · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Clonal Spread of Hospital-Acquired NDM-1-ProducingAntibiotics (Basel, Switzerland) · 2023
    Article
  15. Article
  16. Genomic Characteristics of Carbapenem-ResistantInfection and drug resistance · 2023
    Article
  17. Article
  18. Article
  19. Clinical features and molecular epidemiology of carbapenem-resistantZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

L YinDepartment of Nosocomial Infection Control, Children's Hospital of Fudan University, Shanghai, China.
L HeClinical Microbiology Laboratory, Children's Hospital of Fudan University, Shanghai, China.
J MiaoDepartment of Nosocomial Infection Control, Children's Hospital of Fudan University, Shanghai, China.
W YangDepartment of Nosocomial Infection Control, Children's Hospital of Fudan University, Shanghai, China.
X WangDepartment of Nosocomial Infection Control, Children's Hospital of Fudan University, Shanghai, China.
J MaDepartment of Nosocomial Infection Control, Children's Hospital of Fudan University, Shanghai, China.
N WuDepartment of Nosocomial Infection Control, Children's Hospital of Fudan University, Shanghai, China.
Y CaoNeonatal Intensive Care Unit, Children's Hospital of Fudan University, Shanghai, China.
C WangDepartment of Nosocomial Infection Control and the Clinical Microbiology Laboratory, Children's Hospital of Fudan University, Shanghai, China.
Children's Hospital of Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundColonization has been reported to play an important role in carbapenem-resistant Enterobacterales (CRE) infection; however, the extent to which carriers develop clinical CRE infection and related risk factors in neonatal intensive care unit (NICU) patients is unclear.

aimTo investigate the frequency of CRE colonization and its contribution to infections in NICU patients.

methodsCRE colonization screening and CRE infection surveillance were performed in the NICU in 2017 and 2018.

findingsAmong 1230 unique NICU patients who were screened for CRE colonization, 144 patients tested positive (11.7%, 144/1230), with 9.2% (110/1197) in the intestinal tract, which was higher than that in the upper respiratory tract (6.6%, 62/945) (

conclusionsThe colonization of CRE may increase the incidence of corresponding CRE infection in NICU patients. Receiving mechanical ventilation, malnutrition and critical conditions with high SNAP-II scores were independent risk factors for subsequent CR-KP clinical infection.

Indexed as

ColonizationCRENDM-1NICURisk factors for infectionST17

Identifiers

PMID34647006
PMCPMC8498732
OpenAlexW3162452658

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.