Evidence map›Paper›PMID 34646951›Full record

ReviewClinical and translational radiation oncology2021

Cardiac radioablation in the treatment of ventricular tachycardia.

Michael Siedow, Jeremy Brownstein, Rahul N Prasad, Emefah Loccoh, Thura T Harfi, Toshimasa Okabe, Matthew S Tong, Muhammad R Afzal, Terence Williams

Abstract readReview
In one paragraph

Review in Clinical and translational radiation oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Michael SiedowDepartment of Radiation Oncology, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Jeremy BrownsteinDepartment of Radiation Oncology, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Rahul N PrasadDepartment of Radiation Oncology, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Emefah LoccohDepartment of Radiation Oncology, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Thura T HarfiDivision of Cardiovascular Medicine, The Ohio State University Medical Center, Columbus, OH, USA.
Toshimasa OkabeDivision of Cardiovascular Medicine, The Ohio State University Medical Center, Columbus, OH, USA.
Matthew S TongDivision of Cardiovascular Medicine, The Ohio State University Medical Center, Columbus, OH, USA.
Muhammad R AfzalDivision of Cardiovascular Medicine, The Ohio State University Medical Center, Columbus, OH, USA.
Terence WilliamsDepartment of Radiation Oncology, City of Hope National Medical Center, Duarte, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac radioablation with SBRT is a very promising non-invasive modality for the treatment of refractory VT and potentially other cardiac arrhythmias. Initial reports indicate that it is relatively safe and associated with excellent responses, particularly in reduction of ICD-related events, need for anti-arrhythmic medications, and resulting in significantly improved quality of life for patients. Establishment of objective criteria for candidates for cardiac radioablation will accelerate the adoption of this important radiation therapy modality in the treatment of refractory VT and other cardiac arrhythmias in the coming years. In addition, in order to develop more prospective safety and efficacy data, treatment of patients should ideally be performed in the context of clinical trials or prospective registries at, or in collaboration with, experienced centers. Taken together, the future of cardiac radioablation is rich and worthy of further investigation to become a standard treatment in the armamentarium against refractory VT.

Indexed as

Cardiac arrhythmiasCardiac mappingCardiac radioablationSBRTVentricular tachycardia

Identifiers

PMID34646951
PMCPMC8498093

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.