Evidence map›Paper›PMID 34646942›Full record

ArticleHealth science reports2021

Etiology of viral respiratory tract infections in hospitalized adults, and evidence of the high frequency of prehospitalization antibiotic treatment in Norway.

Sara Debes, Jon Birger Haug, Birgitte Freiesleben de Blasio, Christine Monceyron Jonassen, Susanne Gjeruldsen Dudman

Open access · goldAbstract read
In one paragraph

Article in Health science reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Sara DebesØstfold Hospital Trust, Center for Laboratory Medicine Sarpsborg Norway.ORCID https://orcid.org/0000-0002-6342-2601
Jon Birger HaugDepartment of Infection Control Østfold Hospital Trust Sarpsborg Norway.
Birgitte Freiesleben de BlasioDepartment of Methods Development and Analytics, Division of Infection Control and Environmental Health Norwegian Institute of Public Health Oslo Norway.
Christine Monceyron JonassenØstfold Hospital Trust, Center for Laboratory Medicine Sarpsborg Norway.
Susanne Gjeruldsen DudmanFaculty of Medicine Institute of Clinical Medicine, University of Oslo Oslo Norway.ORCID https://orcid.org/0000-0001-5047-4982
Østfold Hospital Trust · NONorwegian Institute of Public Health · NOOslo University Hospital · NOUniversity of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsRespiratory tract infections (RTIs) cause considerable morbidity and mortality in all age groups, but the epidemiology and role of several of the viral RTIs in the adult and elderly patients are still unclear, as is the extent of prehospitalization antibacterial drug use in this population.

methodsWe conducted a three-year (2015-2018) observational study of viral RTIs in hospitalized patients in a 500-bed hospital in Southeastern Norway, including all patients ≥18 years with RTI symptoms where one of the following viral agents was detected in a respiratory specimen (Seegene Allplex): Influenza A/B, RSV A/B, human metapneumovirus (hMPV), adenovirus and parainfluenza virus 1-4. Viral findings, demographical data, and information on prehospital antibiotic prescriptions were recorded.

resultsIn 1182 patients 1222 viral infection events occurred. The mean patient age was 69.6 years, and 53% were females. Influenza virus A/B (63%), RSV A/B (15%) and hMPV (13%) were the most common agents detected. The proportional burden of influenza A H1 was found to be relatively high (65%) in the age groups <69 years, compared to older patients (

conclusionsWe found a high rate of prehospital antibiotic prescription in adults hospitalized with viral RTIs, warranting better stewardship programs to tackle the increasing antibiotic resistance problem.

Indexed as

adultsantibioticetiologyhospitalizationhuman metapneumovirusinfluenzarespiratory syncytial virusviral respiratory tract infection

Identifiers

PMID34646942
PMCPMC8499681
OpenAlexW3206629029

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.