Evidence map›Paper›PMID 34646933›Full record

ArticleInternational journal of cardiology. Heart & vasculature2021

Remote magnetic navigation shows superior long-term outcomes in pediatric atrioventricular (nodal) tachycardia ablation compared to manual radiofrequency and cryoablation.

Anna M E Noten, Janneke A E Kammeraad, Nawin L Ramdat Misier, Sip Wijchers, Ingrid M van Beynum, Michiel Dalinghaus, Thomas B Krasemann, Sing-Chien Yap, Natasja M S de Groot, Tamas Szili-Torok

Open access · goldAbstract read
In one paragraph

Article in International journal of cardiology. Heart & vasculature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Optimal power settings have major impact on procedural efficiency in pulmonary vein isolation guided by robotic magnetic navigation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Anna M E NotenDepartment of Cardiology, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.
Janneke A E KammeraadDepartment of Pediatric Cardiology, Sophia Children's Hospital, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.
Nawin L Ramdat MisierDepartment of Cardiology, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.
Sip WijchersDepartment of Cardiology, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.
Ingrid M van BeynumDepartment of Pediatric Cardiology, Sophia Children's Hospital, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.
Michiel DalinghausDepartment of Pediatric Cardiology, Sophia Children's Hospital, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.
Thomas B KrasemannDepartment of Pediatric Cardiology, Sophia Children's Hospital, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.
Sing-Chien YapDepartment of Cardiology, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.
Natasja M S de GrootDepartment of Cardiology, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.
Tamas Szili-TorokDepartment of Cardiology, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.
Erasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCatheter ablation (CA) is the first-choice treatment for tachyarrhythmia in children. Currently available CA techniques differ in mechanism of catheter navigation and energy sources. There are no large studies comparing long-term outcomes between available CA techniques in a pediatric population with atrioventricular reentry tachycardia (AVRT) or atrioventricular nodal reentry tachycardia (AVNRT) mechanisms.

objectiveThis study aimed to compare procedural and long-term outcomes of remote magnetic navigation-guided radiofrequency (RF) ablation (RMN), manual-guided RF ablation (MAN) and manual-guided cryoablation (CRYO).

methodsThis single-center, retrospective study included all first consecutive CA procedures for AVRT or AVNRT performed in children without structural heart disease from 2008 to 2019. Three study groups were defined by the ablation technique used: RMN, MAN or CRYO. Primary outcome was long-term recurrence of tachyarrhythmia.

resultsIn total, we included 223 patients, aged 14 (IQR 12-16) years; weighting 56 (IQR 47-65) kilograms. In total, 108 procedures were performed using RMN, 76 using MAN and 39 using CRYO. RMN had significantly lower recurrence rates compared to MAN and CRYO at mean follow-up of 5.5 ± 2.9 years (AVRT: 4.3% versus 15.6% versus 54.5%, P < 0.001; AVNRT: 7.7% versus 8.3% versus 35.7%, P = 0.008; for RMN versus MAN versus CRYO respectively). In AVNRT ablation, RMN had significantly lower fluoroscopy doses compared to CRYO [30 (IQR 20-41) versus 45 (IQR 29-65) mGy, P = 0.040).

conclusionIn pediatric patients without structural heart disease who underwent their first AV(N)RT ablation, RMN has superior long-term outcomes compared to MAN and CRYO, in addition to favorable fluoroscopy doses.

Indexed as

AP, accessory pathwayAtrioventricular nodal reentry tachycardiaAtrioventricular reentry tachycardiaAVNRT, atrioventricular nodal reentry tachycardiaAVRT, atrioventricular reentry tachycardiaCA, catheter ablationCatheter ablationCHD, congenital heart defectCryoablationCRYO, cryoablationDAP, dose area productEAM, electro-anatomic mappingECG, electrocardiogramMAN, manualPediatricsRadiofrequency ablationRemote magnetic navigationRF, radiofrequencyRMN, remote magnetic navigationSupraventricular tachycardiaSVT, supraventricular tachycardia

Identifiers

PMID34646933
PMCPMC8495098
OpenAlexW3201760937

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.