Evidence map›Paper›PMID 34646781›Full record

ArticleFrontiers in oncology2021

Decreased CD8

Run Wang, Yifu Song, Tianhao Hu, Xiaoliang Wang, Yang Jiang, Di Zhang, Juanhan Yu, Sheng Han, Liang Kan

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. New insights on anti-tumor immunity of CD8Journal of translational medicine · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Run WangDepartment of Neurosurgery, The First Hospital of China Medical University, Shenyang, China.
Yifu SongDepartment of Neurosurgery, The First Hospital of China Medical University, Shenyang, China.
Tianhao HuDepartment of Neurosurgery, The First Hospital of China Medical University, Shenyang, China.
Xiaoliang WangDepartment of Neurosurgery, The First Hospital of China Medical University, Shenyang, China.
Yang JiangDepartment of Neurosurgery, The First Hospital of China Medical University, Shenyang, China.
Di ZhangDepartment of Pathology, China Medical University, Shenyang, China.
Juanhan YuDepartment of Pathology, China Medical University, Shenyang, China.
Sheng HanDepartment of Neurosurgery, The First Hospital of China Medical University, Shenyang, China.
Liang KanDepartment of Geriatrics, Shengjing Hospital of China Medical University, Shenyang, China.
First Hospital of China Medical University · CNChina Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMultifocal and multicentric glioblastomas (mGBMs) are associated with a poorer prognosis compared to unifocal glioblastoma (uGBM). The presence of CD8

methodsThe clinical data of 57 consecutive IDH wildtype primary mGBM patients with histopathological diagnoses were retrospectively reviewed. CD8

resultsNo significant difference in the concentration of CD8

conclusionsDecreased CD8

Indexed as

CD8chemotherapyMultifocal gliomaprognosistumor-infiltrating lymphocytes (TILs)

Identifiers

PMID34646781
PMCPMC8503598
OpenAlexW3204397886

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.