Evidence map›Paper›PMID 34646628›Full record

ArticleCureus2021

Sodium-Glucose Co-transporter-2 Inhibitor-Induced Pruritus: Itching for Answers.

Kabeer Ali, Saeed R Mohammed, Rishi Deonarine, Surujpal Teelucksingh

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Observational
  2. Role of sodium-glucose cotransporter 2 inhibitors in liver diseases.World journal of experimental medicine · 2025
    Review
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 3 countries.

Kabeer AliInternal Medicine, Eric Williams Medical Sciences Complex, Champs Fleurs, TTO.
Saeed R MohammedFaculty of Clinical Medical Sciences, University of the West Indies, Trinidad, TTO.
Rishi DeonarineInternal Medicine, Medical Associates Hospital, St. Joseph, TTO.
Surujpal TeelucksinghFaculty of Clinical Medical Sciences, University of the West Indies, Trinidad, TTO.
St. Joseph Medical Center in Tacoma · USUniversity of the West Indies · TTUniversity of the West Indies System · JMWilliams (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sodium-glucose co-transporter 2 inhibitors (SGLT2-I) have revolutionized the treatment of type 2 diabetes mellitus during the last decade. It has not only proven to be very effective for glycemic control but also has adjunctive effects in the management of heart failure, hypertension, and diabetic nephropathy, and even contributes to weight loss. Another benefit is the apparent lack of major side effects, particularly hypoglycemia, apart from euglycemic diabetic ketoacidosis. The most well-known side effects are genital mycotic infections and urinary tract infections (UTI). Although pruritus is less well known, we highlight in this case study this side effect as notable albeit uncommon so as to sensitize clinicians to its possibility.

Indexed as

chronic pruritusmaculopapular rashsglt-2 inhibitortype 1 diabetes mellitus (t1d)type 2 diabetes

Identifiers

PMID34646628
PMCPMC8480444
OpenAlexW3198832476

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.