Evidence map›Paper›PMID 34646616›Full record

ArticleCureus2021

Associated Factors With Uremic Pruritus in Chronic Hemodialysis Patients: A Single-Center Observational Study.

Muhammad Sohaib Asghar, Fnu Avinash, Manjeet Singh, Muhammad Ali Siddiqui, Syed Adeel Hassan, Shahid Iqbal, Syeda Ghazala Irshad, Mahrukh Zehra, Kainat Siddiqui, Uzma Rasheed

Open access · diamondAbstract read
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Observational
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Muhammad Sohaib AsgharInternal Medicine, Dow University Hospital, Karachi, PAK.
Fnu AvinashMedicine and Surgery, Liaquat National Hospital and Medical College, Karachi, PAK.
Manjeet SinghInternal Medicine, Liaquat National Hospital and Medical College, Karachi, PAK.
Muhammad Ali SiddiquiInternal Medicine, Liaquat National Hospital and Medical College, Karachi, PAK.
Syed Adeel HassanInternal Medicine, University of Louisville, Louisville, USA.
Shahid IqbalForensic Medicine, Bacha Khan Medical College, Mardan, PAK.
Syeda Ghazala IrshadInternal Medicine, Dow University of Health Sciences, Dow International Medical College, Karachi, PAK.
Mahrukh ZehraInternal Medicine, Dow University of Health Sciences, Dow International Medical College, Karachi, PAK.
Kainat SiddiquiInternal Medicine, Dow University of Health Sciences, Dow International Medical College, Karachi, PAK.
Uzma RasheedInternal Medicine, Liaquat National Hospital and Medical College, Karachi, PAK.
Civil Hospital Karachi · PKLiaquat National Hospital · PKUniversity of Louisville · USDow University of Health Sciences · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objectives Uremic pruritus is a recurrent and delicate manifestation in patients suffering from end-stage renal disease. It is a consequence of multiple factors, primarily comprising of metabolic factors and complement activation along with interleukins. The objective of our study was to find out the associated factors of uremic pruritus in chronic hemodialysis patients. The secondary aim was to obtain cut-off values of all the markers predicting pruritus. Materials and methods A cross-sectional observational study was conducted in the nephrology department of a tertiary care hospital including 135 patients. The current occurrence of pruritus was diagnosed on the basis of a validated and reliable scale of pruritus among chronic kidney disease (CKD) patients in the local language. Multivariate logistic regression and receiver operating characteristic analysis were conducted to decipher the required objectives. Results Study participants had a mean age of 56.29 ± 10.51 years with 56.3% males and 43.7% females. Hypertension was frequent comorbidity (75.6%) followed by diabetes (51.9%). Mean body mass index (BMI), duration of CKD diagnosis, and hemodialysis onset were 26.55 ± 5.37 kg/m

Indexed as

chronic kidney diseasedialysisphosphatepotassiumprurituspth

Identifiers

PMID34646616
PMCPMC8481143
OpenAlexW3197354375

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.