Evidence map›Paper›PMID 34646555›Full record

ArticleTherapeutic advances in infectious disease

Standardization of

Rita O Oladele, Akaninyene A Otu, Oluwaseyi J Balogun, Oladayo M Babalola, Augustina O Nwosu, Iriagbonse Iyabo Osaigbovo, Titilayo Gbajabiamila, Nicholas K Irurhe, Samuel A Fayemiwo, Shuwaram A Shettima and 8 more

Open access · goldAbstract read
In one paragraph

Article in Therapeutic advances in infectious disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Chronic respiratory disease
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 13 institutions in 3 countries.

Rita O OladeleDepartment of Medical Microbiology & Parasitology, College of Medicine, University of Lagos, PMB 12003, Lagos, Nigeria.
Akaninyene A OtuDepartment of Internal Medicine, University of Calabar, Calabar, Nigeria.ORCID https://orcid.org/0000-0002-6009-2707
Oluwaseyi J BalogunDepartment of Biomedical Engineering, College of Medicine, University of Lagos, Lagos, Nigeria.
Oladayo M BabalolaDepartment of Biochemistry, College of Medicine, University of Lagos, Lagos, Nigeria.ORCID https://orcid.org/0000-0003-4106-3035
Augustina O NwosuCentral Research Laboratory, College of Medicine, University of Lagos, Lagos, Nigeria.
Iriagbonse Iyabo OsaigbovoDepartment of Medical Microbiology, College of Medical Sciences, University of Benin, Benin City, Nigeria.ORCID https://orcid.org/0000-0001-8111-0743
Titilayo GbajabiamilaNational Institute for Medical Research, Lagos, Nigeria.
Nicholas K IrurheDepartment of Radiology, College of Medicine, University of Lagos, Lagos, Nigeria.
Samuel A FayemiwoDepartment of Medical Microbiology & Parasitology, College of Medicine, University of Ibadan, University College Hospital, Ibadan, Nigeria.
Shuwaram A ShettimaDepartment of Medical Microbiology, Parasitology and Immunology, Federal Medical Centre, Yola, Nigeria.
Nkolika Stella UwaezuokeDepartment of Medical Microbiology, Federal Medical Centre, Abuja, Nigeria.ORCID https://orcid.org/0000-0003-1059-5637
Chinagozi Precious EdwinDepartment of Medical Microbiology, Aminu Kano Teaching Hospital, Kano, Nigeria.
Toyese Stephen AyanbekuDepartment of Medical Microbiology, Federal Medical Centre, Bida, Nigeria.
Joy U OkaaDepartment of Pharmaceutical Microbiology and Biotechnology, Faculty of Pharmaceutical Sciences, Nnamdi Azikiwe University, Awka, Nigeria.
Charles John ElikwuDepartment of Medical Microbiology, Benjamin Carson College of Medicine, Babcock University, Ilishan-Remo, Nigeria.ORCID https://orcid.org/0000-0003-2721-2903
David W DenningNational Aspergillosis Centre, Manchester University NHS Foundation Trust, Manchester, UK.
Phyllis J KankiDepartment of Immunology and Infectious Diseases, Harvard T.H Chan School of Public Health, Harvard University, Boston, MA, USA.
Folasade T OgunsolaDepartment of Medical Microbiology & Parasitology, College of Medicine, University of Lagos, Lagos, Nigeria.
University of Lagos · NGAminu Kano Teaching Hospital · NGBabcock University · NGFederal Medical Centre · NGFederal Medical Centre · NGFederal Medical Centre · NGHarvard University · USLeeds Teaching Hospitals NHS Trust · GBManchester University NHS Foundation Trust · GBNigerian Institute of Medical Research · NGNnamdi Azikiwe University · NGUniversity of Benin · NGUniversity of Ibadan · NG

Funding

Building Research And Innovation in Nigeria's Science - (BRAINS)D43TW010134 · FIC · COLLEGE OF MEDICINE, UNIVERSITY OF LAGOS · PI OGUNSOLA, FOLASADE TOLULOPE · 2015 to 2020
$3.2M
FIC NIH HHS D43 TW010134
6 · The paper itself

Abstract

BACKGROUND AND

objectivesCommercial

methodsSera from 519 prospectively recruited healthy blood donors and 39 previously confirmed cases of CPA were analysed for

resultsAmong healthy blood donors, 141 (27.2%) were aged 16-25 years with median (interquartile range, IQR) of 22 (20-24) years; 304 (58.6%) were aged 26-40 years with median (IQR) of 32 (29-36) years; while 74 (14.2%) were aged 41-60 years with median (IQR) of 46 (44-49.75). Median IgG level in respective age groups were 0.069 (0.009-0.181), 0.044 (0.014-0.202) and 0.056 (0.01-0.265) with no significant difference found in the three age categories (

conclusionThe optimal diagnostic cutoff for diagnosing CPA in Nigerians using the Bordier kit was 0.821 which is lower than the manufacturer's recommended cutoff of 1.0. The determination of this cutoff among Nigerians will significantly enhance accurate identification of CPA and assessment of its true burden in Nigeria.

Indexed as

Aspergillus IgGblood donorschronic pulmonary aspergillosiscutoffNigeria

Identifiers

PMID34646555
PMCPMC8504277
OpenAlexW3206804107

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.