Evidence map›Paper›PMID 34646426›Full record

ArticleOxidative medicine and cellular longevity2021

Serum Fetuin-B Levels Are Elevated in Women with Metabolic Syndrome and Associated with Increased Oxidative Stress.

Shiyao Xue, Hongdong Han, Shunli Rui, Mengliu Yang, Yizhou Huang, Bin Zhan, Shan Geng, Hua Liu, Chen Chen, Gangyi Yang and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
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  6. Cord Blood Fetuin-B, Fetal Growth Factors, and Lipids in Gestational Diabetes Mellitus.The Journal of clinical endocrinology and metabolism · 2025
    Article
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

Shiyao XueKey Laboratory of Diagnostic Medicine (Ministry of Education) and Department of Clinical Biochemistry, College of Laboratory Medicine, Chongqing Medical University, 400016 Chongqing, China.ORCID https://orcid.org/0000-0001-6459-8871
Hongdong HanDepartment of Endocrinology, The Second Affiliated Hospital, Chongqing Medical University, Chongqing 400010, China.ORCID https://orcid.org/0000-0001-7057-0410
Shunli RuiKey Laboratory of Diagnostic Medicine (Ministry of Education) and Department of Clinical Biochemistry, College of Laboratory Medicine, Chongqing Medical University, 400016 Chongqing, China.
Mengliu YangDepartment of Endocrinology, The Second Affiliated Hospital, Chongqing Medical University, Chongqing 400010, China.ORCID https://orcid.org/0000-0003-1896-0002
Yizhou HuangDepartment of Endocrinology, The Second Affiliated Hospital, Chongqing Medical University, Chongqing 400010, China.
Bin ZhanThe Thirteenth People's Hospital of Chongqing, Chongqing 400016, China.
Shan GengDepartment of Endocrinology, The Second Affiliated Hospital, Chongqing Medical University, Chongqing 400010, China.ORCID https://orcid.org/0000-0003-0838-4726
Hua LiuDepartment of Pediatrics, University of Mississippi Medical Center, 2500 North State Street, Jackson, Mississippi, MS 39216-4505, USA.
Chen ChenEndocrinology, SBMS, Faculty of Medicine, University of Queensland, Brisbane 4072, Australia.ORCID https://orcid.org/0000-0003-2104-534X
Gangyi YangDepartment of Endocrinology, The Second Affiliated Hospital, Chongqing Medical University, Chongqing 400010, China.
Ling LiKey Laboratory of Diagnostic Medicine (Ministry of Education) and Department of Clinical Biochemistry, College of Laboratory Medicine, Chongqing Medical University, 400016 Chongqing, China.ORCID https://orcid.org/0000-0002-0087-3034
Dalian Medical University · CNThe University of Queensland · AUChongqing Medical University · CNChongqing University · CNThird People 's Hospital of Chongqing · CNUniversity of Mississippi Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies on serum fetuin-B (fetuin-like protein IRL685) have investigated its association with T2DM; however, the reason for the variation in serum fetuin-B and its regulatory factors in metabolic disease remain unclear. Here, we evaluated serum fetuin-B levels in women with newly diagnosed MetS and performed multiple interventions to investigate the role of fetuin-B in the pathogenesis of MetS. Serum fetuin-B levels were assessed using ELISA. Bioinformatics analysis was performed to analyze fetuin-B-related genes and signaling pathways. Additionally, oxidative stress parameters were measured in the

Indexed as

AdultBiomarkersFemaleFetuin-BHumansInsulin ResistanceMetabolic SyndromeMiddle AgedOxidative StressTriglyceridesYoung AdultBiomarkersFetuin-BTriglycerides

Identifiers

PMID34646426
PMCPMC8505080
OpenAlexW3202333539

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.