Evidence map›Paper›PMID 34646393›Full record

ArticleTheranostics2021

Inhibition of tumor progression and M2 microglial polarization by extracellular vesicle-mediated microRNA-124 in a 3D microfluidic glioblastoma microenvironment.

Soohyun Hong, Jae Young You, Kyurim Paek, Jubin Park, Su Jin Kang, Eun Hee Han, Nakwon Choi, Seok Chung, Won Jong Rhee, Jeong Ah Kim

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Soohyun HongResearch Center for Bioconvergence Analysis, Korea Basic Science Institute, Chungbuk 28119, Republic of Korea.
Jae Young YouCenter for Scientific Instrumentation, Korea Basic Science Institute, Chungbuk 28119, Republic of Korea.
Kyurim PaekCenter for Scientific Instrumentation, Korea Basic Science Institute, Chungbuk 28119, Republic of Korea.
Jubin ParkCenter for Scientific Instrumentation, Korea Basic Science Institute, Chungbuk 28119, Republic of Korea.
Su Jin KangDepartment of Bioengineering and Nano-Bioengineering, Incheon National University, Incheon 22012, Republic of Korea.
Eun Hee HanResearch Center for Bioconvergence Analysis, Korea Basic Science Institute, Chungbuk 28119, Republic of Korea.
Nakwon ChoiBrain Science Institute, Korea Institute of Science and Technology, Seoul 02792, Republic of Korea.
Seok ChungProgram in Biomicro System Technology, Korea University, Seoul 02841, Republic of Korea.
Won Jong RheeDepartment of Bioengineering and Nano-Bioengineering, Incheon National University, Incheon 22012, Republic of Korea.
Jeong Ah KimCenter for Scientific Instrumentation, Korea Basic Science Institute, Chungbuk 28119, Republic of Korea.
Incheon National University · KRKorea University · KRKorea Basic Science Institute · KRKorean Association Of Science and Technology Studies · KRKorea University of Science and Technology · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Brain NeoplasmsCell Line, TumorDrug Delivery SystemsExtracellular VesiclesGlioblastomaHEK293 CellsHumansMacrophage ActivationMacrophagesMicrofluidicsMicrogliaMicroRNAsTumor MicroenvironmentMicroRNAsMIRN124 microRNA, humanextracellular vesicleglioblastomamicrogliamicroRNA-124three-dimensional (3D) cell culture

Identifiers

PMID34646393
PMCPMC8490520
OpenAlexW3206238716

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.