Evidence map›Paper›PMID 34646378›Full record

ArticleTheranostics2021

Accelerating precision anti-cancer therapy by time-lapse and label-free 3D tumor slice culture platform.

Fuqiang Xing, Yu-Cheng Liu, Shigao Huang, Xueying Lyu, Sek Man Su, Un In Chan, Pei-Chun Wu, Yinghan Yan, Nana Ai, Jianjie Li and 19 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. CDK4/6 Inhibition Induces CD8Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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  15. Proteasome: Role in T Cell Function Regulation.International journal of biological sciences · 2025
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Making In Vitro Tumor Models Whole Again.Advanced healthcare materials · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors at 3 institutions in 2 countries.

Fuqiang XingCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Yu-Cheng LiuCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Shigao HuangCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Xueying LyuCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Sek Man SuCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Un In ChanCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Pei-Chun WuCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Yinghan YanCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Nana AiCentre of Reproduction, Development and Aging, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Jianjie LiCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Ming ZhaoCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Barani Kumar RajendranCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Jianlin LiuCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Fangyuan ShaoCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Heng SunCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Tak Kan ChoiCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Wenli ZhuKiang Wu Hospital, Macau SAR, China.
Guanghui LuoKiang Wu Hospital, Macau SAR, China.
Shuiming LiuKiang Wu Hospital, Macau SAR, China.
De Li XuKiang Wu Hospital, Macau SAR, China.
Kin Long ChanKiang Wu Hospital, Macau SAR, China.
Qi ZhaoCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Kai MiaoCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Kathy Qian LuoCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Wei GeMOE Frontier Science Centre for Precision Oncology, University of Macau, Macau SAR, China.
Xiaoling XuCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Guanyu WangDepartment of Biology, School of Life Sciences & Guangdong Provincial Key Laboratory of Computational Science and Material Design, Southern University of Science and Technology, Shenzhen, China.
Tzu-Ming LiuCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
Chu-Xia DengCancer Center, Faculty of Health Sciences, University of Macau, Macau SAR, China.
City University of Macau · MOUniversity of Macau · MOKiang Wu Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The feasibility of personalized medicine for cancer treatment is largely hampered by costly, labor-intensive and time-consuming models for drug discovery. Herein, establishing new pre-clinical models to tackle these issues for personalized medicine is urgently demanded.

Indexed as

AnimalsAntineoplastic AgentsCell Line, TumorCell ProliferationChinaDrug DiscoveryDrug Screening Assays, AntitumorHigh-Throughput Screening AssaysHumansMiceNeoplasmsOptical ImagingPrecision MedicinePrimary Cell CultureTime-Lapse ImagingTumor MicroenvironmentAntineoplastic Agents3D tumor slice cultureapoptosisFRET techniquelabel-freepersonalized medicine

Identifiers

PMID34646378
PMCPMC8490519
OpenAlexW3207428367

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.