Evidence map›Paper›PMID 34646292›Full record

ArticleFrontiers in plant science2021

Impact of Specific

Jennifer Schwestka, Julia König-Beihammer, Yun-Ji Shin, Ulrike Vavra, Nikolaus F Kienzl, Clemens Grünwald-Gruber, Daniel Maresch, Miriam Klausberger, Elisabeth Laurent, Maria Stadler and 13 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in plant science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 16 citations in OpenAlex.

  1. Mass Spectrometric Analysis ofMolecules (Basel, Switzerland) · 2026
    Article
  2. Review
  3. Article
  4. EngineeringBiotechnology reports (Amsterdam, Netherlands) · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Product safety aspects of plant molecular farming.Frontiers in bioengineering and biotechnology · 2023
    Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 5 institutions in 1 country.

Jennifer SchwestkaDepartment of Applied Genetics and Cell Biology, Institute of Plant Biotechnology and Cell Biology, University of Natural Resources and Life Sciences, Vienna, Austria.
Julia König-BeihammerDepartment of Applied Genetics and Cell Biology, Institute of Plant Biotechnology and Cell Biology, University of Natural Resources and Life Sciences, Vienna, Austria.
Yun-Ji ShinDepartment of Applied Genetics and Cell Biology, Institute of Plant Biotechnology and Cell Biology, University of Natural Resources and Life Sciences, Vienna, Austria.
Ulrike VavraDepartment of Applied Genetics and Cell Biology, Institute of Plant Biotechnology and Cell Biology, University of Natural Resources and Life Sciences, Vienna, Austria.
Nikolaus F KienzlDepartment of Applied Genetics and Cell Biology, Institute of Plant Biotechnology and Cell Biology, University of Natural Resources and Life Sciences, Vienna, Austria.
Clemens Grünwald-GruberDepartment of Chemistry, Institute of Biochemistry, University of Natural Resources and Life Sciences, Vienna, Austria.
Daniel MareschDepartment of Chemistry, Institute of Biochemistry, University of Natural Resources and Life Sciences, Vienna, Austria.
Miriam KlausbergerDepartment of Biotechnology, University of Natural Resources and Life Sciences, Vienna, Austria.
Elisabeth LaurentDepartment of Biotechnology, University of Natural Resources and Life Sciences, Vienna, Austria.
Maria StadlerInstitute of Immunology, University of Veterinary Medicine, Vienna, Austria.
Gabriele ManhartInstitute for Medical Biochemistry, University of Veterinary Medicine, Vienna, Austria.
Jasmin HuberCompetence Unit Molecular Diagnostics, Center for Health and Bioresources, AIT Austrian Institute of Technology GmbH, Vienna, Austria.
Manuela HofnerCompetence Unit Molecular Diagnostics, Center for Health and Bioresources, AIT Austrian Institute of Technology GmbH, Vienna, Austria.
Klemens VierlingerCompetence Unit Molecular Diagnostics, Center for Health and Bioresources, AIT Austrian Institute of Technology GmbH, Vienna, Austria.
Andreas WeinhäuselCompetence Unit Molecular Diagnostics, Center for Health and Bioresources, AIT Austrian Institute of Technology GmbH, Vienna, Austria.
Ines SwobodaBiotechnology Section, FH Campus Wien, University of Applied Sciences, Vienna, Austria.
Christoph J BinderDepartment of Laboratory Medicine, Medical University of Vienna, Vienna, Austria.
Wilhelm GernerInstitute of Immunology, University of Veterinary Medicine, Vienna, Austria.
Florian GrebienInstitute for Medical Biochemistry, University of Veterinary Medicine, Vienna, Austria.
Friedrich AltmannDepartment of Chemistry, Institute of Biochemistry, University of Natural Resources and Life Sciences, Vienna, Austria.
Lukas MachDepartment of Applied Genetics and Cell Biology, Institute of Plant Biotechnology and Cell Biology, University of Natural Resources and Life Sciences, Vienna, Austria.
Eva StögerDepartment of Applied Genetics and Cell Biology, Institute of Plant Biotechnology and Cell Biology, University of Natural Resources and Life Sciences, Vienna, Austria.
Richard StrasserDepartment of Applied Genetics and Cell Biology, Institute of Plant Biotechnology and Cell Biology, University of Natural Resources and Life Sciences, Vienna, Austria.
BOKU University · ATAustrian Institute of Technology · ATUniversity of Veterinary Medicine Vienna · ATFH Campus Wien · ATMedical University of Vienna · AT

Funding

Austrian Science Fund FWF P 31920Austrian Science Fund FWF W 1224
6 · The paper itself

Abstract

The receptor binding domain (RBD) of the SARS-CoV-2 spike protein plays a key role in the virus-host cell interaction, and viral infection. The RBD is a major target for neutralizing antibodies, whilst recombinant RBD is commonly used as an antigen in serological assays. Such assays are essential tools to gain control over the pandemic and detect the extent and durability of an immune response in infected or vaccinated populations. Transient expression in plants can contribute to the fast production of viral antigens, which are required by industry in high amounts. Whilst plant-produced RBDs are glycosylated,

Indexed as

allergenCOVID-19cross-reactive carbohydrate determinantglycosylationposttranslational modificationSARS-CoV-2virus

Identifiers

PMID34646292
PMCPMC8503525
OpenAlexW3202708317

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.