Evidence map›Paper›PMID 34646160›Full record

ArticleFrontiers in physiology2021

Plasma-Derived microRNAs Are Influenced by Acute and Chronic Exercise in Patients With Heart Failure With Reduced Ejection Fraction.

Isabel Witvrouwen, Andreas B Gevaert, Nadine Possemiers, Bert Ectors, Tibor Stoop, Inge Goovaerts, Evi Boeren, Wendy Hens, Paul J Beckers, Anne Vorlat and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Exercise ModulatesInternational journal of molecular sciences · 2026
    Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Cardiopulmonary Exercise Testing in Heart Failure.Journal of cardiovascular development and disease · 2024
    Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Isabel WitvrouwenResearch Group Cardiovascular Diseases, GENCOR, University of Antwerp, Antwerp, Belgium.
Andreas B GevaertResearch Group Cardiovascular Diseases, GENCOR, University of Antwerp, Antwerp, Belgium.
Nadine PossemiersDepartment of Cardiology, Antwerp University Hospital, Edegem, Belgium.
Bert EctorsDepartment of Cardiology, Antwerp University Hospital, Edegem, Belgium.
Tibor StoopDepartment of Cardiology, Antwerp University Hospital, Edegem, Belgium.
Inge GoovaertsDepartment of Cardiology, Antwerp University Hospital, Edegem, Belgium.
Evi BoerenResearch Group Cardiovascular Diseases, GENCOR, University of Antwerp, Antwerp, Belgium.
Wendy HensDepartment of Cardiology, Antwerp University Hospital, Edegem, Belgium.
Paul J BeckersDepartment of Cardiology, Antwerp University Hospital, Edegem, Belgium.
Anne VorlatResearch Group Cardiovascular Diseases, GENCOR, University of Antwerp, Antwerp, Belgium.
Hein HeidbuchelResearch Group Cardiovascular Diseases, GENCOR, University of Antwerp, Antwerp, Belgium.
Amaryllis H Van CraenenbroeckLaboratory of Experimental Medicine and Paediatrics, University of Antwerp, Antwerp, Belgium.
Emeline M Van CraenenbroeckResearch Group Cardiovascular Diseases, GENCOR, University of Antwerp, Antwerp, Belgium.
Antwerp University Hospital · BEUniversity of Antwerp · BEKU Leuven · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

adaptationexercise trainingHFrEF—heart failure with reduced ejection fractionmicroRNApeak oxygen uptakeresponseVO2peak

Identifiers

PMID34646160
PMCPMC8502864
OpenAlexW3202677944

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.