Evidence map›Paper›PMID 34646154›Full record

ArticleFrontiers in physiology2021

Robust Reductions of Body Weight and Food Intake by an Oxytocin Analog in Rats.

Clinton T Elfers, James E Blevins, Elizabeth A Lawson, Richard Pittner, David Silva, Alex Kiselyov, Christian L Roth

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Clinton T ElfersCenter for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, United States.
James E BlevinsVA Puget Sound Health Care System, Office of Research and Development Medical Research Service, Department of Veterans Affairs Medical Center, Seattle, WA, United States.
Elizabeth A LawsonNeuroendocrine Unit, Massachusetts General Hospital and Department of Medicine, Harvard Medical School, Boston, MA, United States.
Richard PittnerOXT Therapeutics, Saint Louis, MO, United States.
David SilvaOXT Therapeutics, Saint Louis, MO, United States.
Alex KiselyovOXT Therapeutics, Saint Louis, MO, United States.
Christian L RothCenter for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, United States.
University of Washington · USHarvard University · US

Funding

Vector and Transgenic Mouse CoreP30DK017047 · NIDDK · UNIVERSITY OF WASHINGTON · PI Karin E Bornfeldt · 1986 to 2026
$41.4M
ROLE OF DIETARY CONSTITUENTS ON GENE EXPRESSION IN INTESTINAL EPITHELIUMP30DK040561 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Elizabeth Austen Lawson, Takara Leah Stanley · 1994 to 2026
$31.6M
Role of Brown Adipose Tissue Thermogenesis in Oxytocin-Elicited Weight LossR01DK115976 · NIDDK · SEATTLE INST FOR BIOMEDICAL/CLINICAL RES · PI BLEVINS, JAMES ERNEST · 2018 to 2021
$1.4M
Novel, Potent and Metabolically Stable Oxytocin Analogues to Treat ObesityR41DK120236 · NIDDK · OXT THERAPEUTICS, INC. · PI ROTH, CHRISTIAN LUDWIG · 2019 to 2019
$279k
NIDDK NIH HHS P30 DK017047NIDDK NIH HHS P30 DK040561NIDDK NIH HHS R01 DK115976NIDDK NIH HHS R41 DK120236
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

body weightdiet-induced obesityfood intakein vivo stabilityoxytocinoxytocin analograts

Identifiers

PMID34646154
PMCPMC8502973
OpenAlexW3201840778

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.