ReviewFrontiers in pharmacology2021
The Adverse Cardiovascular Effects and Cardiotoxicity of Kratom (
Review in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- The effects of kratomFrontiers in pharmacology · 2025Pooled it
- Effects of 7-hydroxymitragynine on serotonin, amino acid profiles, and ion homeostasis in SH-SY5Y cells.Molecular biology reports · 2026Article
- Chronic Kratom Use as a Potential Risk Factor for Embolic Stroke of Undetermined Source: A Case Report.Cureus · 2026Article
- Brugada Syndrome Unmasked by Kratom Use in a Young Man.JACC. Case reports · 2026Article
- Chronic kratom use as a precipitant for acquired Brugada syndrome.HeartRhythm case reports · 2025Article
- Evaluating the drug interactions in kratom usage: clinical application.Expert opinion on drug metabolism & toxicology · 2025Review
- Kratom-Associated Acute Right Ventricular Dysfunction: Diagnostic and Management Insights.JACC. Case reports · 2025Article
- AI-Assisted Hypothesis Generation to Address Challenges in Cardiotoxicity Research: Simulation Study Using ChatGPT With GPT-4o.Journal of medical Internet research · 2025Article
- Kratom Cardiotoxicity: Reversible Brugada Pattern and QTc Prolongation.JACC. Case reports · 2025Article
- A Kratomic Bomb: Cardiotoxicities From Mitragyna speciosa Extract.JACC. Case reports · 2025Article
- Review
- Article
- [Kratom-From natural remedy to addictive drug and back].Der Nervenarzt · 2024Review
- Ventricular fibrillation during football training as a consequence of kratom and caffeine use in an adolescent: case report.European heart journal. Case reports · 2024Article
- Drug testing for mitragynine and kratom: Analytical challenges and medico-legal considerations.Drug testing and analysis · 2023Article
- Article
- Acute, Sublethal, and Developmental Toxicity of Kratom (International journal of environmental research and public health · 2022Article
- Association between kratom (Heliyon · 2022Article
- Adolescent kratom exposure affects cognitive behaviours and brain metabolite profiles in Sprague-Dawley rats.Frontiers in pharmacology · 2022Article
- Kratom Abuse Potential 2021: An Updated Eight Factor Analysis.Frontiers in pharmacology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.