Evidence map›Paper›PMID 34646087›Full record

ArticlePathology oncology research : POR2021

Analysis of the Expression and Prognostic Potential of a Novel Metabolic Regulator ANGPTL8/Betatrophin in Human Cancers.

Fangfang Xu, Dandan Tian, Xiaoyang Shi, Kai Sun, Yuqing Chen

Open access · goldAbstract read
In one paragraph

Article in Pathology oncology research : POR, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Fangfang XuClinical Medical Research Center, Henan Provincial People's Hospital and Zhengzhou University People's Hospital, Zheng Zhou, China.
Dandan TianDepartment of Hypertension, Henan Provincial People's Hospital and Zhengzhou University People's Hospital, Zheng Zhou, China.
Xiaoyang ShiDepartment of Endocrinology, Henan Provincial People's Hospital and Zhengzhou University People's Hospital, Zheng Zhou, China.
Kai SunDepartment of Hematology, Henan Provincial People's Hospital and Zhengzhou University People's Hospital, Zheng Zhou, China.
Yuqing ChenDepartment of Hematology, Henan Provincial People's Hospital and Zhengzhou University People's Hospital, Zheng Zhou, China.
Henan Provincial People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The angiopoietin-like protein (ANGPTL) family members, except for the novel atypical member ANGPTL8/betatrophin, have been reported to participate in angiogenesis, inflammation and cancer. ANGPTL8/betatrophin is a metabolic regulator that is involved in lipid metabolism and glucose homeostasis. However, little is known about the expression and prognostic value of ANGPTL8/betatrophin in human cancers. In this study, we first conducted detailed analyses of ANGPTL8/betatrophin expression in cancer/normal samples

Indexed as

Angiopoietin-Like Protein 8Angiopoietin-like ProteinsBiomarkers, TumorGene Expression ProfilingHep G2 CellsHumansInsulin ResistanceMCF-7 CellsNeoplasmsPeptide HormonesPhosphatidylinositol 3-KinasesPrognosisSignal TransductionAngiopoietin-Like Protein 8Angiopoietin-like ProteinsANGPTL8 protein, humanBiomarkers, TumorPeptide HormonesPhosphatidylinositol 3-KinasesAkt signalingANGPTL8/betatrophindifferential expression analysisglucose homeostasisinflammationlipid metabolismprognostic biomarker

Identifiers

PMID34646087
PMCPMC8502826
OpenAlexW3201840592

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.