Evidence map›Paper›PMID 34646006›Full record

ReviewNature reviews. Microbiology2022

Infectious disease in an era of global change.

Rachel E Baker, Ayesha S Mahmud, Ian F Miller, Malavika Rajeev, Fidisoa Rasambainarivo, Benjamin L Rice, Saki Takahashi, Andrew J Tatem, Caroline E Wagner, Lin-Fa Wang and 2 more

2 registry-linked trialsAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Nature reviews. Microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 788 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
788citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06402227 nacompletednot on this mapstarted 2023, after this paper: background citation

Effectiveness of Board Game on Improving Knowledge, Attitudes and Behavioral Intentions of Infection Control for Senior Elementary School Students: a Randomized Controlled Trial

TypeinterventionalSponsorHU, HUEY-LANRan2023 to 2024Enrolled310ConditionsKnowledge of Infection Control, Attitude of Infection Control, Behavioral Intentions of Infection ControlArmsgamified instruction, conventional lesson lecture
NCT07527247 phase2recruitingnot on this mapstarted 2025, after this paper: background citation

Using AS01 Adjuvant to Improve Immune Response in Older Adults Through Trained Immunity

TypeinterventionalSponsorSingapore General HospitalRan2025 to 2029Enrolled40ConditionsImmune System Responses and Trained Immunity After AS01 Administration, Healthy AdultArmsAS01 adjuvant (0.5 mL intramuscular), YF17D (Stamaril, Sanofi-Pasteur), Placebo (NaCl 09%, 0.5mL)
3 · Its place in the literature

Who cites it

788 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Review
  8. Transient receptor potential channels inChannels (Austin, Tex.) · 2026
    Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Scorpion Peptides in Antiviral Drug Discovery: An In-depth Review.Probiotics and antimicrobial proteins · 2026
    Review
  20. Article

728 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rachel E BakerDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ, USA. racheleb@princeton.edu.ORCID http://orcid.org/0000-0002-2661-8103
Ayesha S MahmudDepartment of Demography, University of California, Berkeley, Berkeley, CA, USA.
Ian F MillerDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ, USA.ORCID http://orcid.org/0000-0002-2673-9618
Malavika RajeevDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ, USA.
Fidisoa RasambainarivoDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ, USA.
Benjamin L RiceDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ, USA.
Saki TakahashiEPPIcenter Program, Division of HIV, ID, and Global Medicine, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.
Andrew J TatemWorldPop, School of Geography and Environmental Science, University of Southampton, Southampton, UK.
Caroline E WagnerDepartment of Bioengineering, McGill University, Montreal, Quebec, Canada.
Lin-Fa WangProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore.ORCID http://orcid.org/0000-0003-2752-0535
Amy WesolowskiDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
C Jessica E MetcalfDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ, USA. cmetcalf@princeton.edu.

Funding

Human mobility models to forecast disease dynamics and the effectiveness of public health interventionsR01AI160780 · NIAID · JOHNS HOPKINS UNIVERSITY · PI CUMMINGS, DEREK A, WESOLOWSKI, AMY · 2021 to 2025
$3.3M
Dev-Core-001P2CHD073964 · NICHD · UNIVERSITY OF CALIFORNIA BERKELEY · PI EDWARD ANDREW MIGUEL · 2019 to 2026
$2.9M
Disease Emergence and Elimination: Using Mobility Data to Inform Spatial Disease DynamicsDP2LM013102 · NLM · JOHNS HOPKINS UNIVERSITY · PI WESOLOWSKI, AMY · 2018 to 2018
$2.5M
Gates Foundation INV-024911NIAID NIH HHS R01 AI160780NICHD NIH HHS P2C HD073964NLM NIH HHS DP2 LM013102
6 · The paper itself

Abstract

The twenty-first century has witnessed a wave of severe infectious disease outbreaks, not least the COVID-19 pandemic, which has had a devastating impact on lives and livelihoods around the globe. The 2003 severe acute respiratory syndrome coronavirus outbreak, the 2009 swine flu pandemic, the 2012 Middle East respiratory syndrome coronavirus outbreak, the 2013-2016 Ebola virus disease epidemic in West Africa and the 2015 Zika virus disease epidemic all resulted in substantial morbidity and mortality while spreading across borders to infect people in multiple countries. At the same time, the past few decades have ushered in an unprecedented era of technological, demographic and climatic change: airline flights have doubled since 2000, since 2007 more people live in urban areas than rural areas, population numbers continue to climb and climate change presents an escalating threat to society. In this Review, we consider the extent to which these recent global changes have increased the risk of infectious disease outbreaks, even as improved sanitation and access to health care have resulted in considerable progress worldwide.

Indexed as

Communicable DiseasesCOVID-19Hemorrhagic Fever, EbolaMiddle East Respiratory Syndrome CoronavirusZika VirusZika Virus InfectionDisease OutbreaksHumansPandemics

Identifiers

PMID34646006
PMCPMC8513385

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.