Evidence map›Paper›PMID 34645960›Full record

ArticleEye (London, England)2022

Evaluation of lacrimal drainage system in Pseudoexfoliation syndrome.

Fatma Corak Eroglu, Mehmet Ali Sekeroglu, Tugce Horozoglu Ceran, Mert Simsek, Gozde Hondur

Open access · bronzeAbstract read
In one paragraph

Article in Eye (London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Fatma Corak ErogluUniversity of Health Sciences, Ulucanlar Eye Education and Research Hospital, Department of Ophthalmology, Ankara, Turkey. dr_fatoscorak@hotmail.com.ORCID 0000-0003-3003-0756
Mehmet Ali SekerogluUniversity of Health Sciences, Ulucanlar Eye Education and Research Hospital, Department of Ophthalmology, Ankara, Turkey.ORCID 0000-0002-0467-1480
Tugce Horozoglu CeranUniversity of Health Sciences, Ulucanlar Eye Education and Research Hospital, Department of Ophthalmology, Ankara, Turkey.ORCID 0000-0003-2132-3098
Mert SimsekUniversity of Health Sciences, Ulucanlar Eye Education and Research Hospital, Department of Ophthalmology, Ankara, Turkey.ORCID 0000-0002-8503-5354
Gozde HondurUniversity of Health Sciences, Ulucanlar Eye Education and Research Hospital, Department of Ophthalmology, Ankara, Turkey.ORCID 0000-0002-3615-8884
Sağlık Bilimleri Üniversitesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the prevalence of the obstruction of lacrimal drainage system (LDS) in patients with pseudoexfoliation (PXF) syndrome. MATERIALS AND

methodsThis cross-sectional study included 152 eyes of 76 consecutive patients with bilateral PXF syndrome and 170 eyes of 85 age and gender-matched controls. The LDS evaluation was performed based on dye disappearance test, slit-lamp examination, diagnostic probing, and irrigation test. The presence of punctal stenosis and canalicular obstruction were considered as the obstruction of proximal LDS; and complete or incomplete nasolacrimal duct obstruction was considered as obstruction of distal LDS. Demographic characteristics, ophthalmologic findings, and prevalence and site of obstruction of LDS were compared among the groups.

resultsThe prevalence of obstruction of LDS was higher in the PXF syndrome group when compared to controls (21.1% vs 12.2%), but the difference was not statistically significant (p = 0.061). The obstruction of proximal LDS was found to be more frequent in the PXF syndrome (17.7%) group when compared to controls (10.0%), and this difference was statistically significant (p = 0.041). There was significantly more punctal stenosis in the PXF syndrome group when compared to controls (15.1% vs 7.6%, p = 0.033). The prevalence of canalicular stenosis and obstruction of distal LDS was similar in the PXF and the control groups (p = 0.596 and p = 0.741, respectively).

conclusionThe prevalence of punctal stenosis was statistically significantly higher in the PXF syndrome group when compared to the controls. This association is probably related to increased local ocular surface inflammation which is triggered by the accumulation of PXF material.

Indexed as

Exfoliation SyndromeEyelid DiseasesLacrimal Duct ObstructionNasolacrimal DuctConstriction, PathologicCross-Sectional StudiesHumans

Identifiers

PMID34645960
PMCPMC8511857
OpenAlexW3205671508

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.