Evidence map›Paper›PMID 34645916›Full record

Trial reportScientific reports2021

Outcomes in high and low volume hospitals in patients with acute hematochezia in a cohort study.

Naoki Ishii, Naoyoshi Nagata, Katsumasa Kobayashi, Atsushi Yamauchi, Atsuo Yamada, Jun Omori, Takashi Ikeya, Taiki Aoyama, Naoyuki Tominaga, Yoshinori Sato and 39 more

Abstract readClinical TrialMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

49 authors.

Naoki IshiiDivision of Gastroenterology, Tokyo Shinagawa Hospital, 6-3-22 Higashi-Ooi, Shinagawa-ku, Tokyo, 140-8522, Japan. naoishi0328@gmail.com.
Naoyoshi NagataDepartment of Gastroenterological Endoscopy, Tokyo Medical University, Tokyo, Japan.
Katsumasa KobayashiDepartment of Gastroenterology, Tokyo Metropolitan Bokutoh Hospital, Tokyo, Japan.
Atsushi YamauchiDepartment of Gastroenterology and Hepatology, Kitano Hospital, Tazuke Kofukai Medical Research Institute, Osaka, Japan.
Atsuo YamadaDepartment of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Jun OmoriDepartment of Gastroenterology, Nippon Medical School, Graduate School of Medicine, Tokyo, Japan.
Takashi IkeyaDepartment of Gastroenterology, St. Luke's International University, Tokyo, Japan.
Taiki AoyamaDepartment of Gastroenterology, Hiroshima City Asa Citizens Hospital, Hiroshima, Japan.
Naoyuki TominagaDepartment of Gastroenterology, Saga Medical Center Koseikan, Saga, Japan.
Yoshinori SatoDivision of Gastroenterology and Hepatology, Department of Internal Medicine, St Marianna University School of Medicine, Kanagawa, Japan.
Takaaki KishinoDepartment of Gastroenterology and Hepatology, Center for Digestive and Liver Diseases, Nara City Hospital, Nara, Japan.
Tsunaki SawadaDepartment of Endoscopy, Nagoya University Hospital, Aichi, Japan.
Masaki MurataDepartment of Gastroenterology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.
Akinari TakaoDepartment of Gastroenterology, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Japan.
Kazuhiro MizukamiDepartment of Gastroenterology, Oita University, Oita, Japan.
Ken KinjoDepartment of Gastroenterology, Fukuoka University Chikushi Hospital, Fukuoka, Japan.
Shunji FujimoriDepartment of Gastroenterology, Chiba Hokusoh Hospital, Nippon Medical School, Chiba, Japan.
Takahiro UotaniDepartment of Gastroenterology, Japanese Red Cross Shizuoka Hospital, Shizuoka, Japan.
Minoru FujitaDivision of Endoscopy and Ultrasonography, Department of Clinical Pathology and Laboratory Medicine, Kawasaki Medical School General Medical Center, Okayama, Japan.
Hiroki SatoDivision of Gastroenterology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.
Sho SuzukiDepartment of Gastroenterology and Hepatology, Center for Digestive Disease and Division of Endoscopy, University of Miyazaki Hospital, Miyazaki, Japan.
Toshiaki NarasakaDepartment of Gastroenterology, University of Tsukuba, Ibaraki, Japan.
Junnosuke HayasakaDepartment of Gastroenterology, Toranomon Hospital, Tokyo, Japan.
Tomohiro FunabikiDepartment of Emergency Medicine, Fujita Health University Hospital, Aichi, Japan.
Yuzuru KinjoDepartment of Gastroenterology, Naha City Hospital, Okinawa, Japan.
Akira MizukiDepartment of Internal Medicine, Tokyo Saiseikai Central Hospital, Tokyo, Japan.
Shu KiyotokiDepartment of Gastroenterology, Shuto General Hospital, Yamaguchi, Japan.
Tatsuya MikamiDivision of Endoscopy, Hirosaki University Hospital, Aomori, Japan.
Ryosuke GushimaDepartment of Gastroenterology and Hepatology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Hiroyuki FujiiDepartment of Gastroenterology and Hepatology, National Hospital Organization Fukuokahigashi Medical Center, Fukuoka, Japan.
Yuta FuyunoDepartment of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Naohiko GunjiDepartment of Gastroenterology, Fukushima Medical University, Fukushima, Japan.
Yosuke ToyaDivision of Gastroenterology, Department of Internal Medicine, Iwate Medical University, Iwate, Japan.
Kazuyuki NarimatsuDepartment of Internal Medicine, National Defense Medical College, Saitama, Japan.
Noriaki ManabeDivision of Endoscopy and Ultrasonography, Department of Clinical Pathology and Laboratory Medicine, Kawasaki Medical School, Okayama, Japan.
Koji NagaikeDepartment of Gastroenterology and Hepatology, Suita Municipal Hospital, Osaka, Japan.
Tetsu KinjoDepartment of Endoscopy, University of the Ryukyus Hospital, Okinawa, Japan.
Yorinobu SumidaDepartment of Gastroenterology, National Hospital Organization Kyushu Medical Center, Fukuoka, Japan.
Sadahiro FunakoshiDepartment of Gastroenterological Endoscopy, Fukuoka University Hospital, Fukuoka, Japan.
Kana KawagishiDepartment of Gastroenterology, School of Medicine, Kitasato University, Kanagawa, Japan.
Tamotsu MatsuhashiDepartment of Gastroenterology and Neurology, Akita University Graduate School of Medicine, Akita, Japan.
Yuga KomakiDigestive and Lifestyle Diseases, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
Kuniko MikiDepartment of Gastroenterological Endoscopy, Tokyo Medical University, Tokyo, Japan.
Kazuhiro WatanabeDepartment of Gastroenterology and Hepatology, National Center for Global Health and Medicine, Tokyo, Japan.
Fumio OmataDivision of Gastroenterology, Tokyo Shinagawa Hospital, 6-3-22 Higashi-Ooi, Shinagawa-ku, Tokyo, 140-8522, Japan.
Yasutoshi ShiratoriDivision of Gastroenterology, Tokyo Shinagawa Hospital, 6-3-22 Higashi-Ooi, Shinagawa-ku, Tokyo, 140-8522, Japan.
Noriatsu ImamuraDivision of Gastroenterology, Tokyo Shinagawa Hospital, 6-3-22 Higashi-Ooi, Shinagawa-ku, Tokyo, 140-8522, Japan.
Takahiko YanoDivision of Gastroenterology, Tokyo Shinagawa Hospital, 6-3-22 Higashi-Ooi, Shinagawa-ku, Tokyo, 140-8522, Japan.
Mitsuru KaiseDepartment of Gastroenterology, Nippon Medical School, Graduate School of Medicine, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Outcomes of acute lower gastrointestinal bleeding have not been compared according to hospital capacity. We aimed to perform a propensity score-matched cohort study with path and mediation analyses for acute hematochezia patients. Hospitals were divided into high- versus low-volume hospitals for emergency medical services. Rebleeding and death within 30 days were compared. Computed tomography, early colonoscopy (colonoscopy performed within 24 h), and endoscopic therapies were included as mediators. A total of 2644 matched pairs were yielded. The rebleeding rate within 30 days was not significant between high- and low-volume hospitals (16% vs. 17%, P = 0.44). The mortality rate within 30 days was significantly higher in the high-volume cohort than in the low-volume cohort (1.7% vs. 0.8%, P = 0.003). Treatment at high-volume hospitals was not a significant factor for rebleeding (odds ratio [OR] = 0.91; 95% confidence interval [CI], 0.79-1.06; P = 0.23), but was significant for death within 30 days (OR = 2.03; 95% CI, 1.17-3.52; P = 0.012) on multivariate logistic regression after adjusting for patients' characteristics. Mediation effects were not observed, except for rebleeding within 30 days in high-volume hospitals through early colonoscopy. However, the direct effect of high-volume hospitals on rebleeding was not significant. High-volume hospitals did not improve the outcomes of acute hematochezia patients.

Indexed as

ColonoscopyGastrointestinal HemorrhageHospitals, High-VolumeHospitals, Low-VolumeAcute DiseaseAgedAged, 80 and overFemaleHumansMaleMiddle AgedRetrospective Studies

Identifiers

PMID34645916
PMCPMC8514573

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.