Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
43 authors at 14 institutions in 2 countries.
Israel Molina *PROSICS Barcelona, Vall d'Hebron University Hospital, Passeig de la Vall d'Hebron, 119, 08035, Barcelona, Spain.ORCID 0000-0001-6642-7515
Milena Soriano Marcolino *Department of Internal Medicine, Medical School and Telehealth Center, University Hospital, Universidade Federal de Minas Gerais, Avenida Professor Alfredo Balena 190 Sala 246, Belo Horizonte, Brazil. milenamarc@ufmg.br.ORCID 0000-0003-4278-3771
Magda Carvalho Pires *Department of Statistics, Universidade Federal de Minas Gerais, Av. Presidente Antônio Carlos, 6627, ICEx, Sala 4071, Belo Horizonte, Brazil.ORCID 0000-0003-3312-4002
Lucas Emanuel Ferreira RamosDepartment of Statistics, Universidade Federal de Minas Gerais, Av. Presidente Antônio Carlos, 6627, ICEx, Sala 4071, Belo Horizonte, Brazil.ORCID 0000-0001-7844-0581
Rafael Tavares SilvaDepartment of Statistics, Universidade Federal de Minas Gerais, Av. Presidente Antônio Carlos, 6627, ICEx, Sala 4071, Belo Horizonte, Brazil.ORCID 0000-0002-9270-5328
Isaias José Ramos de OliveiraMedical School, Universidade Federal de Minas Gerais, Avenida Professor Alfredo Balena, 190, Belo Horizonte, Brazil.ORCID 0000-0001-9232-4309
Rafael Lima Rodrigues de CarvalhoInstitute for Health Technology Assessment (IATS/ CNPq), Rua Ramiro Barcelos, 2359, Prédio 21 | Sala 507, Porto Alegre, Brazil.ORCID 0000-0003-3576-3748
Aline Gabrielle Sousa NunesHospital UNIMED BH, Av. Do Contorno, Belo Horizonte, 3097, Brazil.ORCID 0000-0001-8036-0871
Ana Lara Rodrigues Monteiro de BarrosHospital Metropolitano Doutor Célio de Castro, Rua Dona Luiza, 311, Belo Horizonte, Brazil.ORCID 0000-0002-2612-4744
Ana Luiza Bahia Alves ScottonHospital Regional Antônio Dias, R. Maj. Gote, 1231, Patos de Minas, Brazil.ORCID 0000-0002-5857-2031
Angélica Aparecida Coelho MadureiraHospital Metropolitano Doutor Célio de Castro, Rua Dona Luiza, 311, Belo Horizonte, Brazil.ORCID 0000-0002-8465-5674
Cíntia Alcantara de CarvalhoHospital João XXIII, Av. Professor Alfredo Balena, 400, Belo Horizonte, Brazil.ORCID 0000-0001-8240-2481
Fernanda d'Athayde RodriguesHospital de Clínicas de Porto Alegre, Av. Ramiro Barcellos, 2350, Porto Alegre, Brazil.ORCID 0000-0001-7368-3592
Fernando AnschauHospital Nossa Senhora da Conceição and Hospital Cristo Redentor, Av. Francisco Trein, 326, Porto Alegre, Brazil.ORCID 0000-0002-2657-5406
Fernando Antonio BotoniMedical School, Universidade Federal de Minas Gerais, Avenida Professor Alfredo Balena, 190, Belo Horizonte, Brazil.ORCID 0000-0001-6268-8507
Guilherme Fagundes NascimentoHospital UNIMED BH, Av. Do Contorno, Belo Horizonte, 3097, Brazil.ORCID 0000-0001-9064-7067
Helena DuaniMedical School, Universidade Federal de Minas Gerais, Avenida Professor Alfredo Balena, 190, Belo Horizonte, Brazil.ORCID 0000-0001-9345-018X
Joice Coutinho de AlvarengaHospital João XXIII, Av. Professor Alfredo Balena, 400, Belo Horizonte, Brazil.ORCID 0000-0003-3536-7112
Leila Beltrami MoreiraInstitute for Health Technology Assessment (IATS/ CNPq), Rua Ramiro Barcelos, 2359, Prédio 21 | Sala 507, Porto Alegre, Brazil.ORCID 0000-0002-4730-7988
Liege Barella ZandonáUniversidade do Vale do Taquari (UNIVATES), Av. Avelino Talini, 171, Lajeado, Brazil.ORCID 0000-0001-6697-6426
Luana Fonseca de AlmeidaMedical School, Universidade Federal de Minas Gerais, Avenida Professor Alfredo Balena, 190, Belo Horizonte, Brazil.ORCID 0000-0001-6934-298X
Luana Martins OliveiraInstitute for Health Technology Assessment (IATS/ CNPq), Rua Ramiro Barcelos, 2359, Prédio 21 | Sala 507, Porto Alegre, Brazil.ORCID 0000-0003-4639-4546
Luciane KopittkeHospital Nossa Senhora da Conceição and Hospital Cristo Redentor, Av. Francisco Trein, 326, Porto Alegre, Brazil.ORCID 0000-0002-6606-7756
Luís César de CastroUniversidade do Vale do Taquari (UNIVATES), Av. Avelino Talini, 171, Lajeado, Brazil.ORCID 0000-0003-2379-0167
Luisa Elem Almeida SantosHospital Regional Antônio Dias, R. Maj. Gote, 1231, Patos de Minas, Brazil.ORCID 0000-0003-0264-5497
Máderson Alvares de Souza CabralMedical School, Universidade Federal de Minas Gerais, Avenida Professor Alfredo Balena, 190, Belo Horizonte, Brazil.ORCID 0000-0001-8556-1998
Maria Angélica Pires FerreiraHospital de Clínicas de Porto Alegre, Av. Ramiro Barcellos, 2350, Porto Alegre, Brazil.ORCID 0000-0003-0961-524X
Natália da Cunha Severino SampaioHospital Eduardo de Menezes, R. Dr. Cristiano Rezende, 2213, Belo Horizonte, Brazil.ORCID 0000-0002-5799-8006
Neimy Ramos de OliveiraHospital Eduardo de Menezes, R. Dr. Cristiano Rezende, 2213, Belo Horizonte, Brazil.ORCID 0000-0001-5408-9459
Pedro Ledic AssafHospital Metropolitano Doutor Célio de Castro, Rua Dona Luiza, 311, Belo Horizonte, Brazil.ORCID 0000-0002-8419-5719
Sofia Jarjour Tavares Starling LopesHospital Julia Kubitschek, R. Dr. Cristiano Rezende, 2745, Belo Horizonte, Brazil.ORCID 0000-0002-5010-2916
Tatiani Oliveira FereguettiHospital Eduardo de Menezes, R. Dr. Cristiano Rezende, 2213, Belo Horizonte, Brazil.ORCID 0000-0001-5845-0715
Veridiana Baldon Dos SantosHospital Nossa Senhora da Conceição and Hospital Cristo Redentor, Av. Francisco Trein, 326, Porto Alegre, Brazil.ORCID 0000-0002-9372-5785
Victor Eliel Bastos de CarvalhoHospital Julia Kubitschek, R. Dr. Cristiano Rezende, 2745, Belo Horizonte, Brazil.ORCID 0000-0002-9495-6112
Yuri Carlotto RamiresHospital Bruno Born, Av. Benjamin Constant, 881, Lajeado, Brazil.ORCID 0000-0002-0730-8716
Antonio Luiz Pinho RibeiroDepartment of Internal Medicine, Medical School and Telehealth Center, University Hospital, Universidade Federal de Minas Gerais, Avenida Professor Alfredo Balena 190 Sala 246, Belo Horizonte, Brazil.ORCID 0000-0002-2740-0042
Freddy Antonio Brito MoscosoMedical School of Fundação Educacional do Município de Assis, Av. Getúlio Vargas, 1200, Assis, Brazil.ORCID 0000-0002-4141-7780
Rogério MouraHospital Balbino - Rede D`or São Luiz, R. Angélica Mota, 90, Rio de Janeiro, Brazil.
Carísi Anne PolanczykInstitute for Health Technology Assessment (IATS/ CNPq), Rua Ramiro Barcelos, 2359, Prédio 21 | Sala 507, Porto Alegre, Brazil.ORCID 0000-0002-2447-2577
Maria do Carmo Pereira NunesMedical School, Universidade Federal de Minas Gerais, Avenida Professor Alfredo Balena, 190, Belo Horizonte, Brazil.ORCID 0000-0001-8801-1828
Universidade Federal de Minas Gerais · BRFundação Hospitalar do Estado de Minas Gerais · BRHospital Nossa Senhora da Conceição · BRNational Council for Scientific and Technological Development · BRFaculdade de Ciências Médicas de Minas Gerais · BRHospital de Clínicas de Porto Alegre · BRHospital Risoleta Tolentino Neves · BRPontifícia Universidade Católica de Minas Gerais · BRUnivates · BRCentro Universitário de Patos de Minas · BRD’Or Institute for Research and Education · BRFundação Getulio Vargas · BRInstituto Benjamin Constant · BRVall d'Hebron Hospital Universitari · ES
Funding
Conselho Nacional de Desenvolvimento Científico e Tecnológico 465518/2014-1Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 88887.507149/2020-00Fundação de Amparo à Pesquisa do Estado de Minas Gerais APQ-00208-20
6 · The paper itself
Abstract
Chagas disease (CD) continues to be a major public health burden in Latina America. Information on the interplay between COVID-19 and CD is lacking. Our aim was to assess clinical characteristics and in-hospital outcomes of patients with CD and COVID-19, and to compare it to non-CD patients. Consecutive patients with confirmed COVID-19 were included from March to September 2020. Genetic matching for sex, age, hypertension, diabetes mellitus and hospital was performed in a 4:1 ratio. Of the 7018 patients who had confirmed COVID-19, 31 patients with CD and 124 matched controls were included (median age 72 (64-80) years-old, 44.5% were male). At baseline, heart failure (25.8% vs. 9.7%) and atrial fibrillation (29.0% vs. 5.6%) were more frequent in CD patients than in the controls (p < 0.05). C-reactive protein levels were lower in CD patients compared with the controls (55.5 [35.7, 85.0] vs. 94.3 [50.7, 167.5] mg/dL). In-hospital management, outcomes and complications were similar between the groups. In this large Brazilian COVID-19 Registry, CD patients had a higher prevalence of atrial fibrillation and chronic heart failure compared with non-CD controls, with no differences in-hospital outcomes. The lower C-reactive protein levels in CD patients require further investigation.
Indexed as
AgedAtrial FibrillationBrazilChagas DiseaseCoinfectionCOVID-19C-Reactive ProteinDiabetes MellitusFemaleHospitalizationHospital MortalityHospitalsHumansHypertensionMaleMiddle AgedC-Reactive Protein
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Chagas disease and SARS-CoV-2 coinfection does not lead to worse in-hospital outcomes. · full record | OpenQuestion