Evidence map›Paper›PMID 34645754›Full record

ArticleInternal medicine (Tokyo, Japan)2022

A Clinical Case of Insulinoma Presenting with Postprandial Hypoglycemia in a Patient with a History of Gastric Bypass Surgery.

Ryosuke Hayashida, Kyoichiro Tsuchiya, Tetsuo Sekine, Takashi Momose, Fuminori Sato, Maya Sakurada, Kenji Nishida, Tatsuya Hayashi, Yasuhiro Morita, Haruka Okada and 3 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Ryosuke HayashidaDepartment of Endocrinology and Metabolism, Tokyo Metropolitan Tama Medical Center, Japan.
Kyoichiro TsuchiyaDepartment of Diabetes and Endocrinology, University of Yamanashi Hospital, Japan.
Tetsuo SekineDepartment of Diabetes and Endocrinology, University of Yamanashi Hospital, Japan.
Takashi MomoseDepartment of Endocrinology and Metabolism, Tokyo Metropolitan Tama Medical Center, Japan.
Fuminori SatoDepartment of Endocrinology and Metabolism, Tokyo Metropolitan Tama Medical Center, Japan.
Maya SakuradaDepartment of Endocrinology and Metabolism, Tokyo Metropolitan Tama Medical Center, Japan.
Kenji NishidaDepartment of Endocrinology and Metabolism, Tokyo Metropolitan Tama Medical Center, Japan.
Tatsuya HayashiDepartment of Gastrointestinal and General Surgery, Tokyo Metropolitan Tama Medical Center, Japan.
Yasuhiro MoritaDepartment of Gastrointestinal and General Surgery, Tokyo Metropolitan Tama Medical Center, Japan.
Haruka OkadaDepartment of Pathology, Tokyo Metropolitan Tama Medical Center, Japan.
Noriyoshi FukushimaDepartment of Pathology, Jichi Medical University, Japan.
Tetsuya YamadaDepartment of Molecular Endocrinology and Metabolism, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Japan.
Motoyoshi TsujinoDepartment of Endocrinology and Metabolism, Tokyo Metropolitan Tama Medical Center, Japan.
Tokyo Metropolitan Tama Medical Center · JPUniversity of Yamanashi Hospital · JPJichi Medical University · JPTokyo Medical and Dental University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 61-year-old man with a history of total gastrectomy for cancer with Roux-en-Y reconstruction showed severe postprandial hypoglycemia accompanied by endogenous hyperinsulinemia. Abdominal ultrasonography and contrast-enhanced computed tomography showed no abnormal findings in the pancreas. A selective arterial secretagogue injection test showed the marked induction of serum immunoreactive insulin when calcium was injected into the splenic artery. A pathological analysis following distal pancreatectomy with splenectomy revealed a pancreatic neuroendocrine microadenoma containing insulin-producing cells in the resected pancreas. This case highlights the importance of carefully evaluating refractory and severe hypoglycemia in patients with a history of gastric surgery to exclude insulinoma.

Indexed as

Gastric BypassHypoglycemiaInsulinomaPancreatic NeoplasmsHumansInsulinMaleMiddle AgedPancreatectomyInsulinhypoglycemiainsulinoma

Identifiers

PMID34645754
PMCPMC9107972
OpenAlexW3205539303

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.