Evidence map›Paper›PMID 34645640›Full record

ArticleBMJ case reports2021

Isolated splenic sarcoidosis: a rare cause of hypercalcaemia in a patient with type 1 diabetes.

Hafiz Muhammad Zubair Ullah, Ashutosh Surya, Nicholas Morley, Sajjad Ahmad

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Isolated splenic sarcoidosis: A case report.Anales del sistema sanitario de Navarra · 2025
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Hafiz Muhammad Zubair UllahDeaprtment of Diabetes and Endocrinology, University Hospital of Wales, Cardiff, UK.
Ashutosh SuryaDeaprtment of Diabetes and Endocrinology, University Hospital of Wales, Cardiff, UK.
Nicholas MorleyDepartment of Nuclear Medicine, Velindre Cancer Centre, Cardiff, UK.
Sajjad AhmadDeaprtment of Diabetes and Endocrinology, University Hospital of Wales, Cardiff, UK drsajjad618@yahoo.com.
University Hospital of Wales · GBVelindre Cancer Centre · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 30-year-old man was admitted to Intensive Therapy Unit (ITU) with status epilepticus secondary to severe hypoglycaemia on a background of type 1 diabetes. CT of the brain showed generalised cerebral oedema. He was successfully stepped down to a medical ward after 2 weeks. He was noted to have persistently high calcium, which required multiple doses of pamidronate. Parathyroid hormone level was appropriately low. CT of the thorax, abdomen and pelvis showed mild hepatosplenomegaly with small pathological lymph nodes throughout the abdomen. Bone marrow biopsy was unremarkable. Lymph node biopsy was difficult to achieve, and therefore a positron emission tomography scan was arranged. This showed an enlarged and hypermetabolic spleen. Differential diagnoses at this point included lymphoma and sarcoidosis. He underwent diagnostic splenectomy, and the diagnosis of sarcoidosis was confirmed histologically. Calcium level remained normal 17 months after splenectomy.

Indexed as

Diabetes Mellitus, Type 1HypercalcemiaSarcoidosisSplenic DiseasesAdultHumansMalePamidronatePamidronatechronic renal failureepilepsy and seizures

Identifiers

PMID34645640
PMCPMC8515440
OpenAlexW3207087922

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.