Evidence map›Paper›PMID 34645407›Full record

ArticleBMC cancer2021

Contemporary treatment patterns and survival of cervical cancer patients in Ethiopia.

Biniyam Tefera Deressa, Mathewos Assefa, Ephrem Tafesse, Eva Johanna Kantelhardt, Ivan Soldatovic, Nikola Cihoric, Daniel Rauch, Ahmedin Jemal

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 5 countries.

Biniyam Tefera DeressaAdama Hospital Medical College, Adama, Ethiopia. biniyamtefera.md@gmail.com.
Mathewos AssefaDepartment of Clinical Oncology, College of Health Sciences, Addis Ababa university, Addis Ababa, Ethiopia.
Ephrem TafesseCollege of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Eva Johanna KantelhardtDepartment of Gynaecology and Institute of Clinical Epidemiology, Martin Luther University, Halle an der Saale, Germany.
Ivan SoldatovicInstitute of Medical Statistics and Informatics, Faculty of Medicine, University of Belgrade, Beograd, Serbia.
Nikola CihoricDepartment of Radiation Oncology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Daniel RauchDepartment of Medical Oncology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Ahmedin JemalSurveillance and Health Equity Science, American Cancer Society, Atlanta, Georgia, USA.
University of Bern · CHAdama Science and Technology University · ETAddis Ababa University · ETAmerican Cancer Society · USMartin Luther University Halle-Wittenberg · DEUniversity of Belgrade · RSUniversity of Gondar · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCervical cancer is the second commonly diagnosed cancer and the second leading cause of cancer death in women in Ethiopia, with rates among the highest worldwide. However, there are limited data on cervical cancer treatment patterns and survival in the country. Herein, we examine treatment patterns and survival of cervical cancer patients treated in Tikur Anbessa Hospital Radiotherapy Center (TAHRC), the only hospital with radiotherapy facility in the country.

methodsWomen with histologically verified cervical cancer who were seen in 2014 (January 1, 2014 to December 31, 2014) at TAHRC were included. Information about clinical characteristics and treatments were extracted from the patients' medical record files. The information on vital status was obtained from medical chart and through telephone calls.

resultAmong 242 patients included in the study, the median age at diagnosis was 48 years. The median waiting time for radiotherapy was 5.6 months (range 2 to 9 months). Stage migration occurred in 13% of patients while waiting for radiotherapy. Consequently, the proportion of patients with stage III or IV disease increased from 66% at first consultation to 74% at the initiation of radiotherapy. Among 151 patients treated with curative intent, only 34 (22.5%) of the patients received concurrent chemotherapy while the reaming patients received radiotherapy alone. The 5-year overall survival rate was 28.4% (20.5% in the worst-case scenario). As expected, survival was lower in patients with advanced stage at initiation of radiotherapy and in those treated as palliative care.

conclusionThe survival of cervical cancer patients remains low in Ethiopia because of late presentation and delay in receipt of radiotherapy, leading to stage migration in substantial proportion of the cases. Concerted and coordinated multisectoral efforts are needed to promote early presentation of cervical cancer and to shorten the unacceptable, long waiting time for radiotherapy.

Indexed as

AdultAgedAged, 80 and overAntineoplastic AgentsDisease ProgressionEthiopiaFemaleHumansMiddle AgedNeoplasm StagingSurvival RateTime-to-TreatmentUterine Cervical NeoplasmsAntineoplastic AgentsCervical cancerEthiopiaOverall survivalTikur Anbessa specialized hospital

Identifiers

PMID34645407
PMCPMC8515694
OpenAlexW3131938314

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.