Evidence map›Paper›PMID 34645156›Full record

ReviewZhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns2021

[Research advances on the cholinergic inflammatory reflex and inflammation resolution].

Z Chen, X He, M W Yao, Z Li, X Xu

Open access · greenAbstract readReview
In one paragraph

Review in Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Z ChenBasic Medical School of Army Medical University (the Third Military Medical University), Chongqing 400038, China.
X HeRocket Force Characteristic Medical Center, Beijing 100088, China.
M W YaoDepartment of Stem Cell and Regenerative Medicine, Army Medical Center of PLA, Chongqing 400042, China.
Z LiDepartment of Stem Cell and Regenerative Medicine, Army Medical Center of PLA, Chongqing 400042, China.
X XuDepartment of Stem Cell and Regenerative Medicine, Army Medical Center of PLA, Chongqing 400042, China.
Army Medical University · CNPLA Rocket Force University of Engineering · CN

Funding

Emergency Special Project of 2019 Novel Coronavirus Infection and Prevention and Control of Chongqing Education Commission of China KYYJ202009Military Pre-research Project of Army Medical University 2019XYY21Youth Science Foundation of National Natural Science Foundation of China 81501666Youth Science Foundation of National Natural Science Foundation of China 81801585
6 · The paper itself

Abstract

The vagus nerve plays an important role in regulating the homeostasis of inflammation. Inflammation signals in the body are passed to the vagus nerve efferent fibers via nerve reflexes, and the signals generated by efferent fibers will play an anti-inflammatory role in various inflammatory diseases through immune cells such as T cells that express choline acetyltransferase and macrophages. However, the resolution of inflammation is not only the interaction between pro-inflammatory and anti-inflammatory cytokines, but also an active process of biosynthesis, including the synthesis of various pro-resolving mediators and their physiological utility process. Moreover, the cholinergic inflammation reflex also plays a crucial role in inflammation resolution. This review reviews and summarizes the cholinergic inflammatory reflex and its key role in the process of inflammation resolution.

Indexed as

InflammationReflexCholinergic AgentsCytokinesHumansVagus NerveCholinergic AgentsCytokines

Identifiers

PMID34645156
PMCPMC11917218
OpenAlexW3205297331

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.