ArticleNeuron2021
Spatial modulation of hippocampal activity in freely moving macaques.
Article in Neuron, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
73 citing papers in PubMed, 130 citations in OpenAlex.
- Mental Scene and Memory Construction and the Hippocampus.Hippocampus · 2026Article
- Physiological landmarks reveal the laminar organization of the primate hippocampus.bioRxiv : the preprint server for biology · 2026Article
- Hippocampal mechanisms underlying the resolution of competition in memory and perception.Nature communications · 2026Article
- From lab to ocean: bridging swimming energetics and wild movements to understand red drum (Sciaenops ocellatus) behavior in a tidal estuary.The Journal of experimental biology · 2026Article
- Distributed neural codes of the 3D position in the marmoset frontal cortex and hippocampus.Nature communications · 2026Article
- Heading and Then Saccades Predict Visual Discrimination Decisions in Freely Moving Ferrets.eNeuro · 2026Article
- Divergent neural representations of space and task between physical and virtual navigation in macaques.Nature communications · 2026Article
- Primate neuroethology: a new synthesis.Trends in cognitive sciences · 2026Review
- Explicitly acquired interrelations among mental schema reduces cognitive load and facilitates emergence of novel responses in mice and artificial neural networks.Experimental brain research · 2026Article
- Neural geometry in the human hippocampus enables generalization across spatial position and gaze.ArXiv · 2026Article
- Eye movements reflect memory-related theta activity in the human brain.PLoS biology · 2026Article
- The Visual Umwelt of primates and Hippocampal Representations of Space.Hippocampus · 2026Review
- Clarifying the neural circuit mechanisms of spontaneous social behavior in macaques.Frontiers in neural circuits · 2026Article
- The Map's Design: Evolution's Impact on Navigation and Spatial Cognition.Animals : an open access journal from MDPI · 2025Review
- Belief embodiment through eye movements facilitates memory-guided navigation.Nature communications · 2025Article
- Multisensory coding of self-motion and its contribution to navigation.Nature reviews. Neuroscience · 2025Review
- Article
- Optogenetic modulation of long-range cortical circuits in awake nonhuman primates.Nature protocols · 2025Review
- Large-scale high-density brain-wide neural recording in nonhuman primates.Nature neuroscience · 2025Article
- Article
13 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
The hippocampal formation is linked to spatial navigation, but there is little corroboration from freely moving primates with concurrent monitoring of head and gaze stances. We recorded neural activity across hippocampal regions in rhesus macaques during free foraging in an open environment while tracking their head and eye. Theta activity was intermittently present at movement onset and modulated by saccades. Many neurons were phase-locked to theta, with few showing phase precession. Most neurons encoded a mixture of spatial variables beyond place and grid tuning. Spatial representations were dominated by facing location and allocentric direction, mostly in head, rather than gaze, coordinates. Importantly, eye movements strongly modulated neural activity in all regions. These findings reveal that the macaque hippocampal formation represents three-dimensional (3D) space using a multiplexed code, with head orientation and eye movement properties being dominant during free exploration.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.