ArticleScience advances2021
Ancestral circuits for vertebrate color vision emerge at the first retinal synapse.
Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 63 citations in OpenAlex.
- A heterogeneous population code at the first synapse of vision.Nature communications · 2026Article
- Article
- Descattering and image restoration with a transformer-based neural network in deep tissue imaging.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- On analogies in vertebrate and insect visual systems.Nature reviews. Neuroscience · 2025Review
- A standardized nomenclature for the rods and cones of the vertebrate retina.PLoS biology · 2025Article
- Morphology and connectivity of retinal horizontal cells in two avian species.Frontiers in cellular neuroscience · 2025Article
- The vertebrate retina: a window into the evolution of computation in the brain.Current opinion in behavioral sciences · 2024Review
- Ancient origin of the rod bipolar cell pathway in the vertebrate retina.Nature ecology & evolution · 2024Article
- Ultraviolet vision in anemonefish improves colour discrimination.The Journal of experimental biology · 2024Article
- More than double the fun with two-photon excitation microscopy.Communications biology · 2024Review
- From water to land: Evolution of photoreceptor circuits for vision in air.PLoS biology · 2024Article
- Ancient origin of the rod bipolar cell pathway in the vertebrate retina.Research square · 2023Article
- Ancient origin of the rod bipolar cell pathway in the vertebrate retina.bioRxiv : the preprint server for biology · 2023Article
- Birds multiplex spectral and temporal visual information via retinal On- and Off-channels.Nature communications · 2023Article
- Amacrine cells differentially balance zebrafish color circuits in the central and peripheral retina.Cell reports · 2023Article
- Article
- Differential encoding of temporally evolving color patterns across nearby V1 neurons.Frontiers in cellular neuroscience · 2023Article
- Evolution of central neural circuits: state of the art and perspectives.Nature reviews. Neuroscience · 2022Review
- Opponent processing in the retinal mosaic of nymphalid butterflies.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
- Sustained deep-tissue voltage recording using a fast indicator evolved for two-photon microscopy.Cell · 2022Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
Abstract
For color vision, retinal circuits separate information about intensity and wavelength. In vertebrates that use the full complement of four “ancestral” cone types, the nature and implementation of this computation remain poorly understood. Here, we establish the complete circuit architecture of outer retinal circuits underlying color processing in larval zebrafish. We find that the synaptic outputs of red and green cones efficiently rotate the encoding of natural daylight in a principal components analysis–like manner to yield primary achromatic and spectrally opponent axes, respectively. Blue cones are tuned to capture most remaining variance when opposed to green cones, while UV cone present a UV achromatic axis for prey capture. We note that fruitflies use essentially the same strategy. Therefore, rotating color space into primary achromatic and chromatic axes at the eye’s first synapse may thus be a fundamental principle of color vision when using more than two spectrally well-separated photoreceptor types.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.