Evidence map›Paper›PMID 34643861›Full record

ArticleInternational urology and nephrology2022

Association of albumin to creatinine ratio with urinary arsenic and metal exposure: evidence from NHANES 2015-2016.

Humairat H Rahman, Danielle Niemann, Stuart H Munson-McGee

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In one paragraph

Article in International urology and nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
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  3. Risk assessment of complex organoarsenic species in food.EFSA journal. European Food Safety Authority · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Humairat H RahmanNew Mexico State University, Las Cruces, NM, 88003, USA. hrahman@nmsu.edu.ORCID http://orcid.org/0000-0002-2483-9607
Danielle NiemannBurrell College of Osteopathic Medicine, Las Cruces, NM, USA.ORCID http://orcid.org/0000-0003-2023-9855
Stuart H Munson-McGeeData Forward Analytics, LLC, Principal, Las Cruces, NM, USA.
EP Analytics (United States) · USNew Mexico State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeUrinary metals can be used to identify metal exposure in humans from various sources in the environment. Decreased renal function and cardiovascular dysfunction may occur due to low levels of metal exposure in the general population. The purpose of this study is to assess the association between urinary arsenic and metals and a higher albumin to creatinine ratio (ACR) among adults in the general US population.

methodsWe conducted a cross sectional analyses using the 2015-2016 National Health and Nutrition Examination Survey (NHANES) dataset. Multiple linear logistic models were used to examine the association between 21 urinary arsenic and metal concentrations (arsenous acid, arsenic acid, arsenobetaine, arsenocholine, dimethylarsinic acid, monomethylarsonic acid, total arsenic, mercury, barium, cadmium, cobalt, cesium, molybdenum, manganese, lead, antinomy, tin, strontium, thallium, tungsten, uranium) and increased ACR (≥ 30 mg/g).

resultsThe sample included 4122 adults, of whom approximately 9.4% of males and 10.7% females had increased ACRs. The exposure included urinary arsenic compounds (7) and urinary metal compounds (14) at or above the limit of detection. Urinary dimethylarsinic acid [OR 38.9, 95% CI 3.6-414.6], urinary monomethylarsonic acid [OR 18.6, 95% CI 1.1-308.2], urinary cadmium [OR 11.9, 95% CI 1.2-122.0], urinary cesium [OR 17.0, 95% CI 2.7-105.8], and urinary antimony [OR 10.7, 95% CI 2.2-51.3] were associated with an increased ACR. No other urinary metals were significantly associated with increased ACR.

conclusionIncreased ACR was positively associated with urinary dimethylarsinic acid, monomethylarsonic acid, cadmium, cesium, and antimony.

Indexed as

ArsenicAdultAlbuminsAntimonyCacodylic AcidCadmiumCesiumCreatinineCross-Sectional StudiesEnvironmental ExposureFemaleHumansMaleMetalsNutrition SurveysAlbuminsAntimonyArsenicCacodylic AcidCadmiumCesiumCreatinineMetalsAlbuminuriaAntimonyCadmiumNHANESUrinary arsenic exposureUrinary metal exposure

Identifiers

PMID34643861
OpenAlexW3207410606

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.