Evidence map›Paper›PMID 34643802›Full record

ArticleInternational journal of legal medicine2022

Validation of the Applied Biosystems RapidHIT ID instrument and ACE GlobalFiler Express sample cartridge.

Jennifer Churchill Cihlar, Kapema Bupe Kapema, Bruce Budowle

Open access · bronzeAbstract read
In one paragraph

Article in International journal of legal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. DNA forensics at forty: the way forward.International journal of legal medicine · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jennifer Churchill CihlarCenter for Human Identification, University of North Texas Health Science Center, Fort Worth, TX, USA. Jennifer.Cihlar@unthsc.edu.ORCID http://orcid.org/0000-0001-9796-193X
Kapema Bupe KapemaCenter for Human Identification, University of North Texas Health Science Center, Fort Worth, TX, USA.
Bruce BudowleCenter for Human Identification, University of North Texas Health Science Center, Fort Worth, TX, USA.
University of North Texas · US

Funding

Thermo Fisher Scientific Sponsored Research Agreement RP0223
6 · The paper itself

Abstract

Rapid DNA platforms are fully automated systems capable of processing DNA from biological samples and interpreting the results in approximately 90 minutes with minimal human intervention. With a greater reliance on the system than on the analyst, validation data are especially needed to define the performance and limitations of commercially available Rapid DNA systems. Thus, validation studies of a Rapid DNA workflow consisting of the Applied Biosystems RapidHIT ID Instrument and RapidLINK software with a focus on the ACE GlobalFiler Express Sample Cartridge and reference buccal swabs were performed in accordance with Scientific Working Group on DNA Analysis Methods Validation Guidelines. These validation studies included assessments of sensitivity, contamination, concordance, reproducibility and repeatability, stability, inhibition, mixtures, sample reprocessing, precision, and first-pass success rate. Overall, the current Applied Biosystems RapidHIT ID Instrument with the ACE GlobalFiler Express sample cartridge was found to be a reliable tool for generation of STR profiles from reference-type buccal swabs.

Indexed as

DNA FingerprintingMicrosatellite RepeatsDNAHumansReproducibility of ResultsSoftwareDNAACE cartridgeRapid DNASTRSWGDAMValidation

Identifiers

PMID34643802
PMCPMC8511620
OpenAlexW3207070143

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.