Evidence map›Paper›PMID 34643629›Full record

ArticleOrganic & biomolecular chemistry2021

Flavonoid-based inhibitors of the Phi-class glutathione transferase from black-grass to combat multiple herbicide resistance.

Maria Schwarz, Rebecca F M Eno, Stefanie Freitag-Pohl, Christopher R Coxon, Hannah E Straker, David J Wortley, David J Hughes, Glynn Mitchell, Jenny Moore, Ian Cummins and 5 more

Abstract read
In one paragraph

Article in Organic & biomolecular chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Maria SchwarzDepartment of Chemistry, University of Durham, Science Laboratories, South Road, Durham, DH1 3LE, UK. p.g.steel@durham.ac.uk.
Rebecca F M EnoDepartment of Chemistry, University of Durham, Science Laboratories, South Road, Durham, DH1 3LE, UK. p.g.steel@durham.ac.uk.
Stefanie Freitag-PohlDepartment of Chemistry, University of Durham, Science Laboratories, South Road, Durham, DH1 3LE, UK. p.g.steel@durham.ac.uk.ORCID 0000-0002-1423-8103
Christopher R CoxonDepartment of Chemistry, University of Durham, Science Laboratories, South Road, Durham, DH1 3LE, UK. p.g.steel@durham.ac.uk.
Hannah E StrakerDepartment of Chemistry, University of Durham, Science Laboratories, South Road, Durham, DH1 3LE, UK. p.g.steel@durham.ac.uk.
David J WortleyCentre for Novel Agricultural Products, Department of Biology, University of York, York YO10 5DD, UK.
David J HughesSyngenta, Jealott's Hill International Research Station, Bracknell, Berks RG42 6EY, UK.
Glynn MitchellSyngenta, Jealott's Hill International Research Station, Bracknell, Berks RG42 6EY, UK.
Jenny MooreSyngenta, Jealott's Hill International Research Station, Bracknell, Berks RG42 6EY, UK.
Ian CumminsDepartment of Biosciences, University of Durham, Science Laboratories, South Road, Durham, DH1 3LE, UK.
Nawaporn OnkokesungAgriculture, School of Natural and Environmental Sciences, Newcastle University, Newcastle-upon-Tyne, NE1 7RU, UK.ORCID 0000-0002-5094-5788
Melissa Brazier-HicksAgriculture, School of Natural and Environmental Sciences, Newcastle University, Newcastle-upon-Tyne, NE1 7RU, UK.
Robert EdwardsAgriculture, School of Natural and Environmental Sciences, Newcastle University, Newcastle-upon-Tyne, NE1 7RU, UK.
Ehmke PohlDepartment of Chemistry, University of Durham, Science Laboratories, South Road, Durham, DH1 3LE, UK. p.g.steel@durham.ac.uk.ORCID 0000-0002-9949-4471
Patrick G SteelDepartment of Chemistry, University of Durham, Science Laboratories, South Road, Durham, DH1 3LE, UK. p.g.steel@durham.ac.uk.ORCID 0000-0002-2493-5826

Funding

Biotechnology and Biological Sciences Research Council BB/G006474/1Biotechnology and Biological Sciences Research Council BB/L001489/1Biotechnology and Biological Sciences Research Council BB/R506618/1
6 · The paper itself

Abstract

The evolution and growth of multiple-herbicide resistance (MHR) in grass weeds continues to threaten global cereal production. While various processes can contribute to resistance, earlier work has identified the phi class glutathione-

Indexed as

Enzyme InhibitorsFlavonoidsGlutathione TransferaseHerbicide ResistanceHerbicidesPoaceaeCrystallography, X-RayModels, MolecularMolecular StructureStructure-Activity RelationshipEnzyme InhibitorsFlavonoidsGlutathione TransferaseHerbicides

Identifiers

PMID34643629
PMCPMC8564858

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.