Evidence map›Paper›PMID 34643573›Full record

SynthesisSaudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association

Effectiveness and safety of the different endoscopic resection methods for 10- to 20-mm nonpedunculated colorectal polyps: A systematic review and pooled analysis.

Xin Yuan, Hui Gao, Cenqin Liu, Hongyao Cui, Zhixin Zhang, Jiarong Xie, Hongpeng Lu, Lei Xu

Open access · diamondAbstract readSystematic Review
In one paragraph

Synthesis in Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Quality indicators for colonoscopy.Gastrointestinal endoscopy · 2024
    Guideline
  2. Pooled it
  3. Pooled it
  4. Endoscopic mucosal resection-precuttingWorld journal of gastroenterology · 2022
    Trial
  5. Clinical analysis of coldWorld journal of gastrointestinal surgery · 2025
    Article
  6. Article
  7. Review
  8. Quality Indicators for Colonoscopy.The American journal of gastroenterology · 2024
    Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Xin YuanSchool of Medicine, Ningbo University, Ningbo First Hospital, Zhejiang, China.
Hui GaoSchool of Medicine, Ningbo University, Ningbo First Hospital, Zhejiang, China.
Cenqin LiuDepartment of Gastroenterology, Ningbo First Hospital, Zhejiang, China.
Hongyao CuiDepartment of Gastroenterology, Haishu Second Hospital, Zhejiang, China.
Zhixin ZhangDepartment of Gastroenterology, Ningbo First Hospital, Zhejiang, China.
Jiarong XieDepartment of Gastroenterology, Ningbo First Hospital, Zhejiang, China.
Hongpeng LuDepartment of Gastroenterology, Ningbo First Hospital, Zhejiang, China.
Lei XuDepartment of Gastroenterology, Ningbo First Hospital, Zhejiang, China.
Ningbo First Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe performed a systematic review and pooled analysis to assess the effectiveness and safety of different endoscopic resection methods for 10- to 20-mm nonpedunculated colorectal polyps.

methodsArticles in PubMed, EMBASE, and the Cochrane Library related to the common endoscopic treatment of 10- to 20-mm nonpedunculated polyps published as of April 2020 were searched. Primary outcomes were the R0 resection rate and en bloc resection rate. Secondary outcomes were safety and the recurrence rate. Meta-regression and subgroup analysis were also performed.

resultsA total of 36 studies involving 3212 polyps were included in the final analysis. Overall, the effectiveness of resection methods with a submucosal uplifting effect, including endoscopic mucosal resection (EMR), cold EMR and underwater EMR (UEMR), was better than that of methods without a nonsubmucosal uplifting effect [R0 resection rate, 90% (95% confidence interval (CI) 0.81-0.94, I

conclusionsMethods with submucosal uplifting effects are more effective than those without for resecting 10- to 20-mm nonpedunculated colorectal polyps, and cold EMR is associated with a lower risk of intraprocedural bleeding than other methods. Additional research is needed to verify the advantages of these methods, especially cold EMR.

Indexed as

Colonic PolypsColorectal NeoplasmsEndoscopic Mucosal ResectionColonoscopyHumansColonic polypscolonoscopyendoscopic polypectomymeta-analysissystematic review

Identifiers

PMID34643573
PMCPMC8656331
OpenAlexW3202567187

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.