Evidence map›Paper›PMID 34643479›Full record

ArticleHuman vaccines & immunotherapeutics2021

The comparison of seroconversion rates among different varicella vaccines administered Turkish children; MAV/06 and vOka.

Zuhal Umit, Zumrut Sahbudak Bal, Aysin Zeytinoglu, Tansu Gulbahar Aydogan, Ozlem Bag, Gizem Guner Ozenen, Ferda Ozkinay, Zafer Kurugol

Open access · bronzeAbstract read
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Article in Human vaccines & immunotherapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Zuhal UmitDivision of Infectious Disease, Department of Pediatrics, Medical School of Ege University, Izmir, Turkey.ORCID 0000-0003-4246-5458
Zumrut Sahbudak BalDivision of Infectious Disease, Department of Pediatrics, Medical School of Ege University, Izmir, Turkey.ORCID 0000-0001-9189-8220
Aysin ZeytinogluDepartment of Medical Microbiology, Ege University Faculty of Medicine, İzmir, Turkey.ORCID 0000-0003-4174-9539
Tansu Gulbahar AydoganDepartment of Medical Microbiology, Ege University Faculty of Medicine, İzmir, Turkey.ORCID 0000-0002-3959-426X
Ozlem BagDepartments of Social Pediatrics, Dr Behcet Uz 'Children's Hospital, Izmir, Turkey.ORCID 0000-0003-2178-4695
Gizem Guner OzenenDivision of Infectious Disease, Department of Pediatrics, Medical School of Ege University, Izmir, Turkey.ORCID 0000-0002-9725-7501
Ferda OzkinayDivision of Infectious Disease, Department of Pediatrics, Medical School of Ege University, Izmir, Turkey.
Zafer KurugolDivision of Infectious Disease, Department of Pediatrics, Medical School of Ege University, Izmir, Turkey.
Ege University · TRDr. Behçet Uz Çocuk Hastalıkları Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Varicella is a vaccine-preventable disease, and the incidence of varicella has declined since the introduction of varicella vaccine campaigns. A wild type of varicella zoster virus (VZV) was isolated from a 33-month-old child with varicella in Korea in 1989, a different strain (MAV/06). A live-attenuated varicella vaccine containing strain (MAV/06), Suduvax®, was developed in South Korea in 1994. Turkey introduced the varicella vaccine containing the MAV/06 strain (Varicella Vaccine-GCC, Green Cross, South Korea) in January 2019. Therefore, we aimed to compare the seroconversion rates among MAV/06 vaccine- and vOka-administered children. We prospectively collected blood samples from 98 received vOKA and 98 received MAV/06 children 6 weeks after administration, and seroconversion rates were determined by an indirect fluorescence assay (Anti-VZV IIFT IgG, Euroimmun, Germany). Seroconversion rate was significantly higher in vOka group than MAV/06 group (82.7% vs. 64.3%;

Indexed as

ChickenpoxChickenpox VaccineAntibodies, ViralChildChild, PreschoolHerpesvirus 3, HumanHumansSeroconversionTurkeyVaccines, AttenuatedAntibodies, ViralChickenpox VaccineVaccines, AttenuatedMAV/06seroconversionSuduvaxVaricellavaricella vaccinevOka

Identifiers

PMID34643479
PMCPMC8828065
OpenAlexW3205256829

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.