Evidence map›Paper›PMID 34643172›Full record

ArticleVirulence2021

Streptococcus agalactiae glyceraldehyde-3-phosphate dehydrogenase (GAPDH) elicits multiple cytokines from human cells and has a minor effect on bacterial persistence in the murine female reproductive tract.

Matthew J Sullivan, Kelvin G K Goh, Ruby Thapa, Debasish Chattopadhyay, Deepak S Ipe, Benjamin L Duell, Lahiru Katupitiya, Dean Gosling, Dhruba Acharya, Glen C Ulett

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Virulence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Roles and mechanisms ofVirulence · 2025
    Article
  2. Article
  3. Article
  4. SubcutaneousJournal of veterinary science · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Matthew J SullivanSchool of Pharmacy and Medical Science, Griffith University, Gold Coast, QLD, Australia.ORCID 0000-0003-2276-3132
Kelvin G K GohSchool of Pharmacy and Medical Science, Griffith University, Gold Coast, QLD, Australia.ORCID 0000-0001-8347-2043
Ruby ThapaSchool of Pharmacy and Medical Science, Griffith University, Gold Coast, QLD, Australia.
Debasish ChattopadhyayDepartment of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.ORCID 0000-0001-5262-9140
Deepak S IpeMenzies Health Institute Queensland, Griffith University, Gold Coast, Qld, Australia.
Benjamin L DuellSchool of Pharmacy and Medical Science, Griffith University, Gold Coast, QLD, Australia.
Lahiru KatupitiyaSchool of Pharmacy and Medical Science, Griffith University, Gold Coast, QLD, Australia.
Dean GoslingSchool of Pharmacy and Medical Science, Griffith University, Gold Coast, QLD, Australia.
Dhruba AcharyaSchool of Pharmacy and Medical Science, Griffith University, Gold Coast, QLD, Australia.
Glen C UlettSchool of Pharmacy and Medical Science, Griffith University, Gold Coast, QLD, Australia.
Griffith University · AUUniversity of Alabama at Birmingham · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CytokinesStreptococcus agalactiaeAnimalsFemaleGlyceraldehyde-3-Phosphate DehydrogenasesHumansImmunologic FactorsMiceVirulenceCytokinesGlyceraldehyde-3-Phosphate DehydrogenasesImmunologic Factorscytokineglyceraldehyde-3-phosphate dehydrogenasehost-microbe interactioninnate immune responsepathogenesisStreptococcus agalactiae

Identifiers

PMID34643172
PMCPMC8667900
OpenAlexW3206341748

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.