Evidence map›Paper›PMID 34643103›Full record

ArticlePhysiological genomics2021

Transcriptome analysis reveals disruption of circadian rhythms in late gestation dairy cows may increase risk for fatty liver and reduced mammary remodeling.

Theresa Casey, Aridany M Suarez-Trujillo, Conor McCabe, Linda Beckett, Rebecca Klopp, Luiz Brito, Victor Marco Rocha Malacco, Susan Hilger, Shawn S Donkin, Jacquelyn Boerman and 1 more

Open access · greenAbstract read
In one paragraph

Article in Physiological genomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Theresa CaseyDepartment of Animal Sciences, Purdue University, West Lafayette, Indiana.ORCID 0000-0002-8835-3550
Aridany M Suarez-TrujilloDepartment of Animal Sciences, Purdue University, West Lafayette, Indiana.
Conor McCabeDepartment of Animal Sciences, Purdue University, West Lafayette, Indiana.
Linda BeckettDepartment of Animal Sciences, Purdue University, West Lafayette, Indiana.
Rebecca KloppDepartment of Animal Sciences, Purdue University, West Lafayette, Indiana.
Luiz BritoDepartment of Animal Sciences, Purdue University, West Lafayette, Indiana.
Victor Marco Rocha MalaccoDepartment of Animal Sciences, Purdue University, West Lafayette, Indiana.ORCID 0000-0002-6245-9429
Susan HilgerDepartment of Animal Sciences, Purdue University, West Lafayette, Indiana.
Shawn S DonkinDepartment of Animal Sciences, Purdue University, West Lafayette, Indiana.ORCID 0000-0003-3571-4946
Jacquelyn BoermanDepartment of Animal Sciences, Purdue University, West Lafayette, Indiana.
Karen PlautDepartment of Animal Sciences, Purdue University, West Lafayette, Indiana.
Purdue University West Lafayette · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circadian disruption increased insulin resistance and decreased mammary development in late gestation, nonlactating (dry) cows. The objective was to measure the effect of circadian disruption on transcriptomes of the liver and mammary gland. At 35 days before expected calving (BEC), multiparous dry cows were assigned to either control (CON) or phase-shifted treatments (PS). CON was exposed to 16-h light and 8-h dark. PS was exposed to 16-h light to 8-h dark, but phase of the light-dark cycle was shifted 6 h every 3 days. On

Indexed as

AnimalsCattleCircadian RhythmFatty LiverFemaleGene Expression ProfilingInsulin ResistanceLactationLiverMammary Glands, AnimalPhotoperiodPregnancyRiskTranscriptomecircadian disruptionlivermammarypregnancytranscriptome

Identifiers

PMID34643103
PMCPMC8616597
OpenAlexW3169429898

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.