Evidence map›Paper›PMID 34642991›Full record

SynthesisClinical oral implants research2021

A systematic review and meta-analysis evaluating the survival, the failure, and the complication rates of veneered and monolithic all-ceramic implant-supported single crowns.

Bjarni Elvar Pjetursson, Irena Sailer, Andrey Latyshev, Kerstin Rabel, Ralf-Joachim Kohal, Duygu Karasan

Erratum issuedAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Clinical oral implants research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 58 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. German S3 guideline on implant-supported all-ceramic restorations.International journal of implant dentistry · 2025
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  7. Monolithic Hybrid Abutment Crowns (Screw-Retained) Versus Monolithic Hybrid Abutments With Monolithic Crowns (Adhesively Cemented): Three-Year Data of a Prospective Clinical Split-Mouth Study.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2025
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  16. Optical stability of 3D-printed and milled zirconia after artificial aging and immersion in liquids: An in vitro study.Journal of prosthodontics : official journal of the American College of Prosthodontists · 2026
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4 · The record

Corrections and comments

  • Erratum issued
    2021
5 · Who and what money

Authors and funding

6 authors.

Bjarni Elvar PjeturssonDepartment of Reconstructive Dentistry, Faculty of Odontology, University of Iceland, Reykjavik, Iceland.ORCID https://orcid.org/0000-0002-2063-5092
Irena SailerDivision of Fixed Prosthodontics and Biomaterials, University Clinics for Dental Medicine, University of Geneva, Geneva, Switzerland.ORCID https://orcid.org/0000-0002-4537-7624
Andrey LatyshevDivision of Fixed Prosthodontics and Biomaterials, University Clinics for Dental Medicine, University of Geneva, Geneva, Switzerland.
Kerstin RabelDepartment of Prosthetic Dentistry, Faculty of Medicine, Center for Dental Medicine, Medical Center - University of Freiburg, Freiburg, Germany.
Ralf-Joachim KohalDepartment of Prosthetic Dentistry, Faculty of Medicine, Center for Dental Medicine, Medical Center - University of Freiburg, Freiburg, Germany.ORCID https://orcid.org/0000-0001-7095-4190
Duygu KarasanDivision of Fixed Prosthodontics and Biomaterials, University Clinics for Dental Medicine, University of Geneva, Geneva, Switzerland.ORCID https://orcid.org/0000-0003-4631-2053

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the survival, failure, and complication rates of veneered and monolithic all-ceramic implant-supported single crowns (SCs).

methodsLiterature search was conducted in Medline (PubMed), Embase, and Cochrane Central Register of Controlled Trials until September 2020 for randomized, prospective, and retrospective clinical trials with follow-up time of at least 1 year, evaluating the outcome of veneered and/or monolithic all-ceramic SCs supported by titanium dental implants. Survival and complication rates were analyzed using robust Poisson's regression models.

resultsForty-nine RCTs and prospective studies reporting on 57 material cohorts were included. Meta-analysis of the included studies indicated an estimated 3-year survival rate of veneered-reinforced glass-ceramic implant-supported SCs of 97.6% (95% CI: 87.0%-99.6%). The estimated 3-year survival rates were 97.0% (95% CI: 94.0%-98.5%) for monolithic-reinforced glass-ceramic implant SCs, 96.9% (95% CI: 93.4%-98.6%) for veneered densely sintered alumina SCs, 96.3% (95% CI: 93.9%-97.7%) for veneered zirconia SCs, 96.1% (95% CI: 93.4%-97.8%) for monolithic zirconia SCs and only 36.3% (95% CI: 0.04%-87.7%) for resin-matrix-ceramic (RMC) SCs. With the exception of RMC SCs (p < 0.0001), the differences in survival rates between the materials did not reach statistical significance. Veneered SCs showed significantly (p = 0.017) higher annual ceramic chipping rates (1.65%) compared with monolithic SCs (0.39%). The location of the SCs, anterior vs. posterior, did not influence survival and chipping rates.

conclusionsWith the exception of RMC SCs, veneered and monolithic implant-supported ceramic SCs showed favorable short-term survival and complication rates. Significantly higher rates for ceramic chipping, however, were reported for veneered compared with monolithic ceramic SCs.

Indexed as

Dental ImplantsDental Restoration FailureCeramicsCrownsDental Prosthesis, Implant-SupportedProspective StudiesRetrospective StudiesDental Implantsbiologicalcomplicationsfixed dental prosthesesimplant crownmeta-analysismonolithicsuccesssurvivalsystematic reviewtechnicalveneeredzirconia framework

Identifiers

PMID34642991
PMCPMC9293296

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.