ArticleInfection2021
Long-term health sequelae and quality of life at least 6 months after infection with SARS-CoV-2: design and rationale of the COVIDOM-study as part of the NAPKON population-based cohort platform (POP).
Article in Infection, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers.
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The trial behind it
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Who cites it
21 citing papers in PubMed.
- Long-term trends in Post-COVID severity: a machine learning analysis from the POP/COVIDOM cohort of the German NAPKON Cohort Network.EClinicalMedicine · 2026Article
- Lung Function Impairment after Mild SARS-CoV-2 Infection in Previously Healthy Individuals.Respiration; international review of thoracic diseases · 2026Article
- From infection to intervention: post-acute sequelae of SARS-CoV-2 infection and cardiovascular risk.Inflammopharmacology · 2025Review
- scRNA-seq reveals persistent aberrant differentiation of nasal epithelium driven by TNFα and TGFβ in post-COVID syndrome.Nature communications · 2025Article
- Alterations of the amygdala in post-COVID olfactory dysfunction.Scientific reports · 2025Article
- Subdomains of Post-COVID Syndrome (PCS) - a population-based study.BMC infectious diseases · 2025Article
- Genome-wide association study of post COVID-19 syndrome in a population-based cohort in Germany.Scientific reports · 2025Article
- Factors associated with reduction in quality of life after SARS-CoV-2 infection.Scientific reports · 2025Article
- [Integration of Inventory Data from Cohort and Registry Studies into an Existing Research Network: National Pandemic Cohort Network (NAPKON)].Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)) · 2024Article
- Article
- Interoperable, Domain-Specific Extensions for the German Corona Consensus (GECCO) COVID-19 Research Data Set Using an Interdisciplinary, Consensus-Based Workflow: Data Set Development Study.JMIR medical informatics · 2023Article
- Increased circulating fibronectin, depletion of natural IgM and heightened EBV, HSV-1 reactivation in ME/CFS and long COVID.medRxiv : the preprint server for health sciences · 2023Article
- No Evidence for Myocarditis or Other Organ Affection by Induction of an Immune Response against Critical SARS-CoV-2 Protein Epitopes in a Mouse Model Susceptible for Autoimmunity.International journal of molecular sciences · 2023Article
- Article
- Statistical biases due to anonymization evaluated in an open clinical dataset from COVID-19 patients.Scientific data · 2022Article
- SARS-CoV-2 Invasion and Pathological Links to Prion Disease.Biomolecules · 2022Article
- SARS-CoV-2 and neurodegenerative diseases: what we know and what we don't.Journal of neural transmission (Vienna, Austria : 1996) · 2022Review
- The German National Pandemic Cohort Network (NAPKON): rationale, study design and baseline characteristics.European journal of epidemiology · 2022Review
- Exposure modality influences viral kinetics but not respiratory outcome of COVID-19 in multiple nonhuman primate species.PLoS pathogens · 2022Article
- The Pathogenesis and Long-Term Consequences of COVID-19 Cardiac Injury.JACC. Basic to translational science · 2022Review
Corrections and comments
- Erratum issued
Authors and funding
41 authors.
Funding
Abstract
purposeOver the course of COVID-19 pandemic, evidence has accumulated that SARS-CoV-2 infections may affect multiple organs and have serious clinical sequelae, but on-site clinical examinations with non-hospitalized samples are rare. We, therefore, aimed to systematically assess the long-term health status of samples of hospitalized and non-hospitalized SARS-CoV-2 infected individuals from three regions in Germany.
methodsThe present paper describes the COVIDOM-study within the population-based cohort platform (POP) which has been established under the auspices of the NAPKON infrastructure (German National Pandemic Cohort Network) of the national Network University Medicine (NUM). Comprehensive health assessments among SARS-CoV-2 infected individuals are conducted at least 6 months after the acute infection at the study sites Kiel, Würzburg and Berlin. Potential participants were identified and contacted via the local public health authorities, irrespective of the severity of the initial infection. A harmonized examination protocol has been implemented, consisting of detailed assessments of medical history, physical examinations, and the collection of multiple biosamples (e.g., serum, plasma, saliva, urine) for future analyses. In addition, patient-reported perception of the impact of local pandemic-related measures and infection on quality-of-life are obtained.
resultsAs of July 2021, in total 6813 individuals infected in 2020 have been invited into the COVIDOM-study. Of these, about 36% wished to participate and 1295 have already been examined at least once.
conclusionNAPKON-POP COVIDOM-study complements other Long COVID studies assessing the long-term consequences of an infection with SARS-CoV-2 by providing detailed health data of population-based samples, including individuals with various degrees of disease severity.
trial registrationRegistered at the German registry for clinical studies (DRKS00023742).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.